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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-type lectin domain containing 7A
Summary
- Gene Symbol
-
- CLEC7A
- Aliases
-
- CD369
- DECTIN-1
- SCARE2
- hDectin-1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Lectin
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0S2Z5Q1 |
|
| Q9BXN2 |
|
| Q68D78 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| detection of molecule of fungal origin | ||
| positive regulation of DNA-binding transcription factor activity | ||
| positive regulation of tumor necrosis factor production | ||
| positive regulation of superoxide anion generation |
GO Hierarchy
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of respiratory burst
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of respiratory burst
- positive regulation of cell population proliferation
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of cell population proliferation
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| metal ion binding | ||
| (1->3)-beta-D-glucan binding | ||
| identical protein binding | ||
| MHC protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- c-type lectin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| C-type lectin fold |
| C-type lectin-like/link domain superfamily |
| C-type lectin-like |
KEGG BRITE Database
Disease
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000962 | Hyperkeratosis |
| HP:0000988 | Skin rash |
| HP:0000989 | Pruritus |
| HP:0001231 | Abnormal fingernail morphology |
| HP:0001250 | Seizure |
| HP:0001597 | Abnormality of the nail |
| HP:0001821 | Broad nail |
| HP:0002105 | Hemoptysis |
| HP:0002205 | Recurrent respiratory infections |
| HP:0002715 | Abnormality of the immune system |
| Disease ID | Disease Name |
|---|---|
| OMIM:613108 |
|
| ORPHA:1334 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 56644 | MGI:1861431 | MOUSE49227 | ||
| 178506 | WB:WBGene00009156 | |||
| 473361 | 9598_0:003644 | PANTR05154 | ||
| 502902 | RGD:1565140 | RATNO31509 | ||
| 532865 | BOVIN30277 | |||
| 611385 | CANLF11077 | |||
| 678685 | SHEEP14909 | |||
| 100038025 | PIGXX26194 | |||
| 100053863 | HORSE37727 | |||
| 100339146 | RABIT12262 |
