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solute carrier family 13 member 3

Summary

Gene Symbol

SLC13A3

Organism

Homo sapiens (human)

External Links

NCBI Gene

64849

PubChem

64849

Alliance of Genome Resources

HGNC:14430

Annotation

Keyword

Alternative splicing
Cell membrane
Disease variant
Glycoprotein
Lipid transport
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8WWT9	Na(+)-coupled carboxylate transporter 3 Sodium-dependent high-affinity dicarboxylate transporter 2 Solute carrier family 13 member 3
B4DF27

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
succinate transmembrane transport	IBA IDA TAS	10992006 21264516 24247155 26176240
dicarboxylic acid transport	IDA TAS	10992006
glutathione transmembrane transport	IDA	24247155
transport across blood-brain barrier	NAS	30280653
alpha-ketoglutarate transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

glutathione transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

glutathione transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

organic substance transport [inference]

lipid transport

organic anion transport [inference]

glutathione transport [inference]

glutathione transmembrane transport

carboxylic acid transport [inference]

dicarboxylic acid transport

C4-dicarboxylate transport [inference]

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

tricarboxylic acid transport [inference]

citrate transport

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport

C4-dicarboxylate transport [inference]

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

tricarboxylic acid transport [inference]

citrate transport

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

nitrogen compound transport [inference]

citrate transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IDA TAS
basolateral plasma membrane	IDA	27053689
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
glutathione transmembrane transporter activity	IDA	24247155
protein binding	IPI	32296183
sodium:dicarboxylate symporter activity	IBA IDA TAS	10992006
alpha-ketoglutarate transmembrane transporter activity	IDA	30635937
succinate transmembrane transporter activity	IBA IDA TAS	10992006 21264516 24247155 26176240 30635937

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

tricarboxylic acid transmembrane transporter activity [inference]

citrate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

succinate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

tricarboxylic acid transmembrane transporter activity [inference]

citrate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

succinate transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050667	alcohol-related neurodevelopmental disorder	Alliance of Genome Resources
DOID:0111668	Kohlschutter-Tonz syndrome	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Macaca mulatta	706364		MACMU02005
Saccharomyces cerevisiae S288C	850403	SGD:S000000633
Saccharomyces cerevisiae S288C	853241	SGD:S000003734
Saccharomyces cerevisiae S288C	855747	SGD:S000005296
Monodelphis domestica	100029726		MONDO03294
Equus caballus	100071226		HORSE20724
Ornithorhynchus anatinus	100074512		ORNAN25674
Taeniopygia guttata	100220067		TAEGU12061
Oryctolagus cuniculus	100355238		RABIT14866
Callithrix jacchus	100387605		CALJA32909