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solute carrier family 13 member 3

Summary

Gene Symbol

SLC13A3

Organism

Homo sapiens (human)

External Links

NCBI Gene

64849

PubChem

64849

Alliance of Genome Resources

HGNC:14430

Annotation

Keyword

Alternative splicing
Cell membrane
Disease variant
Glycoprotein
Lipid transport
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8WWT9	Na(+)-coupled carboxylate transporter 3 Sodium-dependent high-affinity dicarboxylate transporter 2 Solute carrier family 13 member 3
B4DF27

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
succinate transmembrane transport	IBA IDA TAS	10992006 21264516 24247155 26176240
dicarboxylic acid transport	IDA TAS	10992006
glutathione transmembrane transport	IDA	24247155
transport across blood-brain barrier	NAS	30280653
alpha-ketoglutarate transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

glutathione transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

glutathione transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

organic substance transport [inference]

lipid transport

organic anion transport [inference]

glutathione transport [inference]

glutathione transmembrane transport

carboxylic acid transport [inference]

dicarboxylic acid transport

C4-dicarboxylate transport [inference]

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

tricarboxylic acid transport [inference]

citrate transport

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport

C4-dicarboxylate transport [inference]

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

tricarboxylic acid transport [inference]

citrate transport

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

succinate transmembrane transport

nitrogen compound transport [inference]

citrate transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IDA TAS
basolateral plasma membrane	IDA	27053689
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
glutathione transmembrane transporter activity	IDA	24247155
protein binding	IPI	32296183
sodium:dicarboxylate symporter activity	IBA IDA TAS	10992006
alpha-ketoglutarate transmembrane transporter activity	IDA	30635937
succinate transmembrane transporter activity	IBA IDA TAS	10992006 21264516 24247155 26176240 30635937

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

tricarboxylic acid transmembrane transporter activity [inference]

citrate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

succinate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

tricarboxylic acid transmembrane transporter activity [inference]

citrate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

succinate transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium:dicarboxylate symporter activity

high-affinity sodium:dicarboxylate symporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050667	alcohol-related neurodevelopmental disorder	Alliance of Genome Resources
DOID:0111668	Kohlschutter-Tonz syndrome	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of 88 in total

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Species	Gene ID	Orthologous MAtrix
Heterocephalus glaber	101712910	HETGA16855
Ficedula albicollis	101816716	FICAL08178
Melopsittacus undulatus	101873510	MELUD11813
Chrysemys picta bellii	101937109	CHRPI17936
Chinchilla lanigera	102017174	CHILA11828
Capra hircus	102185757	CAPHI04312
Latimeria chalumnae	102346390	LATCH10367
Myotis lucifugus	102438011	MYOLU06520
Pelodiscus sinensis	102447365	PELSI12138
Callorhinchus milii	103186285	CALMI34283