solute carrier family 6 member 4

Summary
Gene Symbol
  • SLC6A4
Organism
Homo sapiens (human)
NCBI Gene
6532
PubChem
6532
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Antiport
  • Cell junction
  • Cell membrane
  • Cell projection
  • Disulfide bond
  • Endosome
  • Glycoprotein
  • Metal-binding
  • Neurotransmitter transport
  • Phosphoprotein
  • Reference proteome
  • Sodium
  • Synapse
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
B2R7Y7
P31645
  • 5HT transporter
  • Solute carrier family 6 member 4
Gene Ontology (GO)
Displaying entries 1 - 5 of 35 in total
GO Term Evidence Code PMID
response to hypoxia
neurotransmitter transport
amino acid transport
response to nutrient
memory
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Transporter
Functional Category
  • E: Amino acid transport and metabolism
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying 1 entry
Gene Ontology
symporter activity
Displaying all 2 entries
InterPro
Sodium
Sodium
Disease
Disease Ontology
Displaying entries 1 - 10 of 21 in total
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050848 obstructive sleep apnea
DOID:0060131 alexithymia
DOID:10933 obsessive-compulsive disorder
DOID:1094 attention deficit hyperactivity disorder
DOID:114 heart disease
DOID:12206 dengue hemorrhagic fever
DOID:12849 autistic disorder
DOID:14320 generalized anxiety disorder
DOID:1470 major depressive disorder

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025