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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
solute carrier family 6 member 4
Summary
- Gene Symbol
-
- SLC6A4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Antiport
- Cell junction
- Cell membrane
- Cell projection
- Disulfide bond
- Endosome
- Glycoprotein
- Metal-binding
- Neurotransmitter transport
- Phosphoprotein
- Reference proteome
- Sodium
- Synapse
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to cGMP | ||
| response to toxic substance | ||
| sperm ejaculation | ||
| positive regulation of serotonin secretion | ||
| behavioral response to cocaine |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| focal adhesion | ||
| plasma membrane | ||
| membrane raft | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| integrin binding | ||
| sodium ion binding | ||
| actin filament binding | ||
| monoamine transmembrane transporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Transporter
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| symporter activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050848 | obstructive sleep apnea | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0060131 | alexithymia | |
| DOID:0080855 | Parkinsonism | |
| DOID:10933 | obsessive-compulsive disorder | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:114 | heart disease | |
| DOID:12206 | dengue hemorrhagic fever |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 15567 | MGI:96285 | MOUSE03740 | ||
| 25553 | RGD:3714 | RATNO02593 | ||
| 37895 | FB:FBgn0010414 | |||
| 171879 | WB:WBGene00003387 | |||
| 282365 | BOVIN12451 | |||
| 443491 | SHEEP02579 | |||
| 468201 | 9598_0:004856 | PANTR14372 | ||
| 491184 | CANLF19117 | |||
| 574140 | MACMU13694 | |||
| 664719 | ZFIN:ZDB-GENE-060314-1 | DANRE08795 |
