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MIRAGE

trafficking kinesin protein 2

Summary

Gene Symbol

TRAK2

Organism

Homo sapiens (human)

External Links

NCBI Gene

66008

PubChem

66008

Alliance of Genome Resources

HGNC:13206

Annotation

Keyword

Alternative splicing
Coiled coil
Cytoplasm
Endosome
Glycoprotein
Mitochondrion
Phosphoprotein
Reference proteome
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
O60296	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein targeting	IBA
neurogenesis	IBA
vesicle transport along microtubule	IBA
mitochondrion distribution	IBA
anterograde axonal transport of mitochondrion

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrion distribution

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

establishment of protein localization [inference]

protein targeting

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle localization [inference]

mitochondrion localization [inference]

mitochondrion distribution

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

vesicle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
cytoplasm	ISS	12034717
mitochondrion	ISS
mitochondrion	IBA
early endosome	IEA
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

axon cytoplasm

cytosol

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
signaling receptor binding	ISS	12034717
protein binding	IPI	15644324
myosin binding	IBA
GABA receptor binding	NAS	15644324
GABA receptor binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

GABA receptor binding

cytoskeletal protein binding [inference]

myosin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Trafficking kinesin-binding protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
anterograde axonal transport of mitochondrion
mitochondrion distribution
myosin binding
neurogenesis
protein targeting
vesicle transport along microtubule

Displaying **all 2** entries
InterPro
HAP1, N-terminal
Trafficking kinesin-binding protein, C-terminal

Ortholog

Displaying entries **1 - 10** of 90 in total

1

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	22906	FB:FBgn0262872
Xenopus tropicalis	66008	Xenbase:XB-GENE-482545
Drosophila melanogaster	67095	FB:FBgn0262872
Mus musculus	70827	Xenbase:XB-GENE-482545	MOUSE28648
Rattus norvegicus	171086	Xenbase:XB-GENE-482545	RATNO42688
Drosophila melanogaster	316085	FB:FBgn0262872
Canis lupus familiaris	488475		CANLF14118
Bos taurus	523970		BOVIN24568
Danio rerio	560810		DANRE39412
Macaca mulatta	701779		MACMU06840

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: April 7, 2025