SRC proto-oncogene, non-receptor tyrosine kinase

Summary
Gene Symbol
  • SRC
Organism
Homo sapiens (human)
NCBI Gene
6714
PubChem
6714
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Cell adhesion
  • Cell cycle
  • Cell junction
  • Cell membrane
  • Cytoskeleton
  • Disease variant
  • Host-virus interaction
  • Immunity
  • Mitochondrion inner membrane
  • Myristate
  • Nucleus
  • Phosphoprotein
  • Proto-oncogene
  • Reference proteome
  • SH2 domain
  • SH3 domain
  • Tyrosine-protein kinase
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
P12931
  • Proto-oncogene c-Src
  • pp60c-src
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 29 in total
GO Term Evidence Code PMID
podosome
nucleus
nucleoplasm
cytoplasm
mitochondrion
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Kinase
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying all 4 entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
Disease
Disease Ontology
Displaying all 7 entries
DO ID Disease Name Source
DOID:0060074 ductal carcinoma in situ
DOID:10283 prostate cancer
DOID:1588 thrombocytopenia
DOID:219 colon cancer
DOID:234 colon adenocarcinoma
DOID:9256 colorectal cancer
DOID:9352 type 2 diabetes mellitus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025