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Proto-oncogene tyrosine-protein kinase Src
Summary
- UniProt ID
- P12931
- Gene Symbol
-
- SRC
- SRC1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P12931
- PubChem
- P12931
- The Human Metabolome Database
- HMDBP01147
- The O-GlcNAc Database
- P12931
- RaftProt
- P12931
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell adhesion
- Cell cycle
- Cell junction
- Cell membrane
- Cytoskeleton
- Disease variant
- Host-virus interaction
- Immunity
- Mitochondrion inner membrane
- Myristate
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cell cycle |
| cell adhesion |
| signal transduction |
| spermatogenesis |
| learning or memory |
| response to mechanical stimulus |
| negative regulation of gene expression |
| macroautophagy |
| peptidyl-tyrosine phosphorylation |
| cell differentiation |
| GO Term |
|---|
| cytosol |
| caveola |
| membrane raft |
| podosome |
| nucleoplasm |
| late endosome |
| focal adhesion |
| extrinsic component of cytoplasmic side of plasma membrane |
| actin filament |
| plasma membrane |
| GO Term |
|---|
| protein kinase activity |
| protein tyrosine kinase activity |
| signaling receptor binding |
| enzyme binding |
| cadherin binding |
| ATPase binding |
| phospholipase activator activity |
| heme binding |
| nuclear estrogen receptor binding |
| phospholipase binding |
Sequence
MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Glycosylation Sites
G82443XX
G27947YN
G59324HL
G80920RR
G29879MS
G90659AW
G10486CT
G57776ZU
G57317CE
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activated NTRK2 signals through FYN | Homo sapiens |
| Activated NTRK3 signals through PI3K | Homo sapiens |
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| DCC mediated attractive signaling | Homo sapiens |
| Downregulation of ERBB4 signaling | Homo sapiens |
| Downstream signal transduction | Homo sapiens |
| Extra-nuclear estrogen signaling | Homo sapiens |
| G alpha (i) signalling events | Homo sapiens |
| G alpha (s) signalling events | Homo sapiens |
| GAB1 signalosome | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
