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MIRAGE
Activated NTRK2 signals through FYN

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
BDNF:p-5Y-NTRK2 homodimerBDNF:p-5Y-NTRK2 homodimer:MyrG-FYN-1MyrG-FynBBDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1ADPATPNR2BBDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1:GRIN2BBDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1:p-Y1474-GRIN2BTrKBp-Y706,Y707-TRKB
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P12931 Proto-oncogene tyrosine-protein kinase Src
  • SRC
  • SRC1
 view
P23560 Neurotrophic factor BDNF precursor form
  • BDNF
 view
Q13224 Glutamate receptor ionotropic, NMDA 2B
  • GRIN2B
  • NMDAR2B
 view
Q16620 BDNF/NT-3 growth factors receptor
  • NTRK2
  • TRKB
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025