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Guidelines
MIRAGE
signal transducer and activator of transcription 1
Summary
- Gene Symbol
-
- STAT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Acetylation
- Activator
- Alternative splicing
- Antiviral defense
- Coiled coil
- Cytoplasm
- DNA-binding
- Direct protein sequencing
- Disease variant
- Host-virus interaction
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- SH2 domain
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P42224 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of endothelial cell proliferation | ||
| positive regulation of mesenchymal cell proliferation | ||
| positive regulation of defense response to virus by host | ||
| positive regulation of defense response to virus by host |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
negative regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of cell population proliferation
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- signal transducer and activator of transcription
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine-mediated signaling pathway |
| receptor signaling pathway via JAK-STAT |
| regulation of cell population proliferation |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111944 | immunodeficiency 31B | |
| DOID:0111945 | immunodeficiency 31A | |
| DOID:0111946 | immunodeficiency 31C | |
| DOID:234 | colon adenocarcinoma | |
| DOID:2526 | prostate adenocarcinoma | |
| DOID:3459 | breast carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115608872 | STRHB03295 | ||
| 116446451 | CORMO24141 | ||
| 116815204 | CHEAB09952 | ||
| 117025725 | RHIFE13958 | ||
| 118898022 | BALMU00530 | ||
| 122226406 | PANLE11264 | ||
| 123798145 | URSAM13012 | ||
| 127488928 | RABIT11863 |
