telomerase reverse transcriptase

Summary
Gene Symbol
  • TERT
Organism
Homo sapiens (human)
NCBI Gene
7015
PubChem
7015
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cytoplasm
  • DNA-binding
  • Disease variant
  • Dyskeratosis congenita
  • Magnesium
  • Metal-binding
  • Nucleus
  • Phosphoprotein
  • RNA-directed DNA polymerase
  • Reference proteome
  • Ribonucleoprotein
  • Telomere
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
O14746
  • HEST2
  • Telomerase catalytic subunit
  • Telomerase-associated protein 2
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
telomerase
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • V: Defense mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 42 in total
DO ID Disease Name Source
DOID:0050156 idiopathic pulmonary fibrosis
DOID:0050685 small cell carcinoma
DOID:0050866 oral squamous cell carcinoma
DOID:0050908 myelodysplastic syndrome
DOID:0060074 ductal carcinoma in situ
DOID:0070016 autosomal dominant dyskeratosis congenita 2
DOID:10283 prostate cancer
DOID:10325 silicosis
DOID:10534 stomach cancer
DOID:11054 urinary bladder cancer

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024