GlyCosmos Portal

Submissions

trefoil factor 1

Summary

Gene Symbol

TFF1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7031

PubChem

7031

Alliance of Genome Resources

HGNC:11755

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Growth factor
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P04155	Breast cancer estrogen-inducible protein PNR-2 Polypeptide P1.A Protein pS2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
carbohydrate metabolic process	TAS	2303034
signal transduction	IEA
cell population proliferation	IEA
negative regulation of cell population proliferation	IEA
response to iron ion	IEA

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

maintenance of gastrointestinal epithelium

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium

developmental process [inference]

cellular developmental process [inference]

cell differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium

response to stimulus [inference]

response to stress [inference]

response to immobilization stress

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to inorganic substance [inference]

response to metal ion [inference]

response to iron ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16189514 21982860 24798994 25416956 32296183
growth factor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

receptor ligand activity [inference]

growth factor activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Trefoil factor 3

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
maintenance of gastrointestinal epithelium

Displaying **all 4** entries
InterPro
P-type trefoil domain superfamily
P-type trefoil domain
P-type trefoil, chordata
P-type trefoil, conserved site

Ortholog

Displaying entries **1 - 10** of 28 in total

1

2

3

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	7031	Xenbase:XB-GENE-5897917
Mus musculus	21784		MOUSE22753
Rattus norvegicus	117270		RATNO22724
Canis lupus familiaris	403491		CANLF12900
Sus scrofa	780401		PIGXX06201
Felis catus	100170654		FELCA22957
Macaca mulatta	100423966		MACMU31977
Pongo abelii	100452689		PONAB21375
Nomascus leucogenys	100595032		NOMLE23782
Pan troglodytes	100613424		PANTR25742

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements