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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
trefoil factor 1
Summary
- Gene Symbol
-
- TFF1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disulfide bond
- Growth factor
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P04155 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to immobilization stress | ||
| cell population proliferation | ||
| response to iron ion | ||
| response to peptide hormone | ||
| negative regulation of cell population proliferation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Trefoil factor 3
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| maintenance of gastrointestinal epithelium |
| InterPro |
|---|
| P-type trefoil domain superfamily |
| P-type trefoil domain |
| P-type trefoil, chordata |
| P-type trefoil, conserved site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060074 | ductal carcinoma in situ | |
| DOID:0060180 | colitis | |
| DOID:0080365 | endometrial hyperplasia | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:10808 | gastric ulcer | |
| DOID:11054 | urinary bladder cancer | |
| DOID:1380 | endometrial cancer | |
| DOID:2394 | ovarian cancer | |
| DOID:2671 | transitional cell carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 21784 | MGI:88135 | MOUSE22753 | ||
| 117270 | RGD:620707 | RATNO22724 | ||
| 403491 | CANLF12900 | |||
| 780401 | PIGXX06201 | |||
| 100127757 | Xenbase:XB-GENE-5897917 | |||
| 100170654 | FELCA22957 | |||
| 100423966 | MACMU31977 | |||
| 100452689 | 9601_0:004f17 | PONAB21375 | ||
| 100595032 | NOMLE23782 | |||
| 100613424 | 9598_0:005302 | PANTR25742 |
