GlyCosmos Portal

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
cytoplasmic vesicle	IDA	15064403
endoplasmic reticulum-Golgi intermediate compartment membrane	TAS
endoplasmic reticulum membrane	TAS
plasma membrane	NAS	10918572
extracellular region	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endoplasmic reticulum-Golgi intermediate compartment membrane

plasma membrane region [inference]

basolateral plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

perinuclear region of cytoplasm

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12297049 15064403 15652357 18757723 24658140 25416956 28988771 31980649 32296183
epidermal growth factor receptor binding	IBA IDA	11278323 6315706
receptor ligand activity	IDA	8702723
transmembrane receptor protein tyrosine kinase activator activity	IEA
growth factor activity	IBA IDA	11278323

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

receptor ligand activity

growth factor activity

growth factor receptor binding [inference]

epidermal growth factor receptor binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

receptor ligand activity

growth factor activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

signaling receptor activator activity [inference]

transmembrane receptor protein tyrosine kinase activator activity

receptor ligand activity

growth factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protransforming growth factor alpha

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
epidermal growth factor receptor signaling pathway
growth factor activity
positive regulation of cell population proliferation
positive regulation of mitotic nuclear division

Displaying 1 entry
InterPro
EGF-like domain

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:2326	gastroenteritis	Alliance of Genome Resources
DOID:3021	acute kidney failure	Alliance of Genome Resources
DOID:3892	insulinoma	Alliance of Genome Resources
DOID:4948	gallbladder carcinoma	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 43** of 43 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Rhinolophus ferrumequinum	117033382		RHIFE24898
Panthera leo	122216172		PANLE02334
Pongo pygmaeus	129030679	9600_0:000ad3

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements