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protein phosphatase 2, regulatory subunit B, beta

Summary

Gene Symbol

Ppp2r2b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

72930

PubChem

72930

Alliance of Genome Resources

MGI:1920180

Annotation

Keyword

Alternative splicing
Apoptosis
Cytoskeleton
Mitochondrion outer membrane
Phosphoprotein
Reference proteome
Repeat
WD repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6ZWR4	PP2A subunit B isoform B55-beta PP2A subunit B isoform PR55-beta PP2A subunit B isoform R2-beta PP2A subunit B isoform beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial fission	ISO
protein targeting to mitochondrion	ISO
apoptotic process	IEA
positive regulation of neuron apoptotic process	ISO
mitochondrial fragmentation involved in apoptotic process	ISO

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial fission

apoptotic mitochondrial changes [inference]

mitochondrial fragmentation involved in apoptotic process

organelle fission [inference]

mitochondrial fission

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

protein targeting to mitochondrion

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein phosphatase type 2A complex	ISO
protein phosphatase type 2A complex	IBA
protein phosphatase type 2A complex	IEA
cytoplasm	ISO
mitochondrion	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 2A complex

cellular anatomical entity [inference]

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein phosphatase regulator activity	IBA
protein phosphatase regulator activity	IEA
protein-containing complex binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein-containing complex binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

phosphatase regulator activity [inference]

protein phosphatase regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
Protein phosphatase 2A regulatory subunit PR55, conserved site
Protein phosphatase 2A regulatory subunit PR55
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5521		HUMAN81543
Rattus norvegicus	60660		RATNO13767
Xenopus tropicalis	72930	Xenbase:XB-GENE-946380
Sus scrofa	397089		PIGXX20030
Pan troglodytes	462170		PANTR36470
Canis lupus familiaris	478053		CANLF06683
Bos taurus	509290		BOVIN33675
Danio rerio	558810		DANRE21720
Macaca mulatta	706988		MACMU39543
Danio rerio	100001644		DANRE06670