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ubiquitously transcribed tetratricopeptide repeat containing, Y-linked

Summary

Gene Symbol

UTY

Organism

Homo sapiens (human)

External Links

NCBI Gene

7404

PubChem

7404

Alliance of Genome Resources

HGNC:12638

Annotation

Keyword

3D-structure
Alternative splicing
Chromatin regulator
Dioxygenase
Direct protein sequencing
Iron
Metal-binding
Nucleus
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
TPR repeat
Zinc

Proteins

Displaying entries **1 - 10** of 28 in total

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UniProt	Protein Name
F4MH92
F4MH60
E1U1M3
F4MH31
F4MH91
F4MH62
O14607	Ubiquitously-transcribed TPR protein on the Y chromosome Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein [histone H3]-trimethyl-L-lysine(27) demethylase UTY
F4MH35
F4MH32
F4MH50

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
heart development	IBA
regulation of gene expression	IBA
chromatin remodeling	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleoplasm	TAS
MLL3/4 complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

histone methyltransferase complex [inference]

MLL3/4 complex

catalytic complex [inference]

transferase complex [inference]

methyltransferase complex [inference]

histone methyltransferase complex [inference]

MLL3/4 complex

cellular anatomical entity [inference]

nucleoplasm

Displaying **all 5** entries
GO Term	Evidence Code	PMID
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
histone demethylase activity	TAS
histone H3K27me2/H3K27me3 demethylase activity	IBA
metal ion binding	IEA
chromatin DNA binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

dioxygenase activity [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

demethylase activity [inference]

protein demethylase activity [inference]

histone demethylase activity

histone H3 demethylase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

catalytic activity, acting on a protein [inference]

protein demethylase activity [inference]

histone demethylase activity

histone H3 demethylase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

histone modifying activity [inference]

histone demethylase activity

histone H3 demethylase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

chromatin binding [inference]

chromatin DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

chromatin DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060473	Kabuki syndrome	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 44 in total

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Species	Gene ID	Orthologous MAtrix
Oryzias latipes	101161131	ORYLA08735
Poecilia formosa	103151380	POEFO17077
Callorhinchus milii	103183921	CALMI03222
Poecilia reticulata	103481677	POERE22493
Rhinopithecus roxellana	104657060	RHIRO35262
Esox lucius	105021924	ESOLU61042
Salmo salar	106575616	SALSA52228
Salmo salar	106581938	SALSA79672
Salmo salar	106586785	SALSA91845
Sinocyclocheilus grahami	107556731	SINGR75907