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peptidase inhibitor 16

Summary

Gene Symbol

Pi16

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74116

PubChem

74116

Alliance of Genome Resources

MGI:1921366

Annotation

Keyword

Alternative splicing
Glycoprotein
Protease inhibitor
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9ET66	Cysteine-rich protease inhibitor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
negative regulation of peptidase activity
negative regulation of cell growth involved in cardiac muscle cell development	ISO	17909105
negative regulation of cell growth involved in cardiac muscle cell development	IDA	17909105

GO Hierarchy

biological process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of developmental growth [inference]

regulation of organ growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of cellular process [inference]

negative regulation of cell growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of multicellular organismal process [inference]

negative regulation of muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of response to stimulus [inference]

regulation of muscle adaptation [inference]

regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of muscle cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of striated muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of developmental growth [inference]

regulation of organ growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of developmental growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of multicellular organismal development [inference]

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cellular process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of muscle cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of striated muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of cellular process [inference]

negative regulation of cell growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle hypertrophy [inference]

regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of muscle adaptation [inference]

regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of organ growth [inference]

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of multicellular organismal process [inference]

negative regulation of muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of organ growth [inference]

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of multicellular organismal development [inference]

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of cell growth involved in cardiac muscle cell development [inference]

negative regulation of cell growth involved in cardiac muscle cell development

negative regulation of heart growth [inference]

negative regulation of cardiac muscle tissue growth [inference]

negative regulation of cell growth involved in cardiac muscle cell development

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IDA	17909105
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying 1 entry
GO Term	Evidence Code	PMID
peptidase inhibitor activity	IEA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Venom allergen

Functional Category

K: Transcription
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
CAP domain
CAP superfamily
Cysteine-rich secretory protein-related

Ortholog

Displaying entries **1 - 10** of 55 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	167	WB:WBGene00021780
Caenorhabditis elegans	10321	WB:WBGene00019179
Caenorhabditis elegans	11571	WB:WBGene00019179
Caenorhabditis elegans	11572	WB:WBGene00017183
Caenorhabditis elegans	51050	WB:WBGene00021780
Caenorhabditis elegans	64827	WB:WBGene00019178
Caenorhabditis elegans	69286	WB:WBGene00019179
Homo sapiens	74116	HGNC:21245
Caenorhabditis elegans	78892	WB:WBGene00021780
Caenorhabditis elegans	83716	WB:WBGene00021780

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