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FIC domain protein adenylyltransferase

Summary

Gene Symbol

FICD

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 743566
PubChem: 743566

Annotation

Keyword

ATP-binding
Membrane
Nucleotidyltransferase
Reference proteome
TPR repeat

Proteins

Displaying **all 3** entries
UniProt	Protein Name
H2Q6T3	AMPylator FICD FIC domain-containing protein
A0A6D2XSB9	AMPylator FICD FIC domain-containing protein
G2HHH4	AMPylator FICD FIC domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
regulation of IRE1-mediated unfolded protein response
response to endoplasmic reticulum stress

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
Hsp70 protein binding
ATP binding
AMPylase activity
protein homodimerization activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

adenylyltransferase activity [inference]

AMPylase activity

binding [inference]

protein binding

heat shock protein binding [inference]

Hsp70 protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-folding chaperone binding [inference]

Hsp70 protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

protein adenylyltransferase FICD

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
AMPylase activity
ATP binding
Hsp70 protein binding
identical protein binding
nucleotide binding
nucleotidyltransferase activity
protein homodimerization activity
protein-folding chaperone binding
regulation of IRE1-mediated unfolded protein response
response to endoplasmic reticulum stress

Displaying **all 5** entries
InterPro
Fido domain-containing protein
Fido domain
Fido-like domain superfamily
Tetratricopeptide repeat
Tetratricopeptide-like helical domain superfamily

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	11153	9606_0:0025a1	HUMAN15194
Mus musculus	231630		MOUSE44982
Rattus norvegicus	288741		RATNO05970
Danio rerio	334648		DANRE36816
Bos taurus	505923		BOVIN09714
Macaca mulatta	706780		MACMU02940
Monodelphis domestica	100025324		MONDO18677
Equus caballus	100059882		HORSE41743
Ornithorhynchus anatinus	100076324		ORNAN14144
Taeniopygia guttata	100232426		TAEGU06117

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Annotation

OrthoDB (Group)

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Acknowledgements