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Wnt family member 5A
Summary
- Gene Symbol
-
- WNT5A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Chondrogenesis
- Developmental protein
- Differentiation
- Disease variant
- Disulfide bond
- Dwarfism
- Extracellular matrix
- Glycoprotein
- Lipoprotein
- Proteomics identification
- Reference proteome
- Signal
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A384N611 |
|
| B3KQX9 |
|
| P41221 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| establishment of planar polarity | ||
| somitogenesis | ||
| kidney development | ||
| epithelial to mesenchymal transition | ||
| neural tube closure |
GO Hierarchy
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- Wnt signaling pathway, calcium modulating pathway
- planar cell polarity pathway involved in axis elongation
- planar cell polarity pathway involved in gastrula mediolateral intercalation
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- planar cell polarity pathway involved in neural tube closure
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- canonical Wnt signaling pathway
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- positive regulation of ossification
- positive regulation of cartilage development
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- Wnt signaling pathway, calcium modulating pathway
- planar cell polarity pathway involved in axis elongation
- planar cell polarity pathway involved in gastrula mediolateral intercalation
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- planar cell polarity pathway involved in neural tube closure
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- canonical Wnt signaling pathway
- planar cell polarity pathway involved in outflow tract morphogenesis
- planar cell polarity pathway involved in ventricular septum morphogenesis
- planar cell polarity pathway involved in cardiac right atrium morphogenesis
- planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
- planar cell polarity pathway involved in pericardium morphogenesis
- positive regulation of ossification
- positive regulation of cartilage development
biological process
cellular process [inference]
establishment or maintenance of cell polarity [inference]
signal transduction [inference]
cell surface receptor signaling pathway [inference]
Wnt signaling pathway
Wnt signaling pathway involved in heart development [inference]
non-canonical Wnt signaling pathway involved in heart development [inference]
planar cell polarity pathway involved in heart morphogenesis [inference]
non-canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
planar cell polarity pathway involved in heart morphogenesis [inference]
non-canonical Wnt signaling pathway involved in heart development [inference]
planar cell polarity pathway involved in heart morphogenesis [inference]
cell surface receptor signaling pathway involved in heart development [inference]
Wnt signaling pathway involved in heart development [inference]
non-canonical Wnt signaling pathway involved in heart development [inference]
planar cell polarity pathway involved in heart morphogenesis [inference]
cellular response to stimulus [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of growth [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of signaling [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
cell surface receptor signaling pathway [inference]
Wnt signaling pathway
Wnt signaling pathway involved in heart development [inference]
non-canonical Wnt signaling pathway involved in heart development [inference]
planar cell polarity pathway involved in heart morphogenesis [inference]
non-canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
planar cell polarity pathway involved in heart morphogenesis [inference]
non-canonical Wnt signaling pathway involved in heart development [inference]
planar cell polarity pathway involved in heart morphogenesis [inference]
cell surface receptor signaling pathway involved in heart development [inference]
Wnt signaling pathway involved in heart development [inference]
non-canonical Wnt signaling pathway involved in heart development [inference]
planar cell polarity pathway involved in heart morphogenesis [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| endoplasmic reticulum lumen | ||
| Golgi lumen |
| GO Term | Evidence Code | PMID |
|---|---|---|
| frizzled binding | ||
| frizzled binding | ||
| frizzled binding | ||
| receptor tyrosine kinase-like orphan receptor binding | ||
| cytokine activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Wnt
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| canonical Wnt signaling pathway |
| cell fate commitment |
| cytokine activity |
| neuron differentiation |
| signaling receptor binding |
| InterPro |
|---|
| Wnt protein, conserved site |
| Wnt, C-terminal domain |
| Wnt |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060766 | autosomal dominant Robinow syndrome 1 |
