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Protein Wnt-5a
Summary
- UniProt ID
- P41221
- Gene Symbol
-
- WNT5A
- Gene ID
- 7474
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Chondrogenesis
- Developmental protein
- Differentiation
- Disease variant
- Disulfide bond
- Dwarfism
- Extracellular matrix
- Glycoprotein
- Lipoprotein
- Reference proteome
- Signal
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| extracellular matrix |
| postsynapse |
| endoplasmic reticulum lumen |
| Golgi lumen |
| cell surface |
| endocytic vesicle membrane |
| extracellular exosome |
Sequence
MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEVYIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 114 | N-linked (GlcNAc...) asparagine | |||
| 120 | N-linked (GlcNAc...) asparagine | |||
| 312 | N-linked (GlcNAc...) asparagine | |||
| 326 | N-linked (GlcNAc...) asparagine |
G70841YG
G83460ZZ
G59626AS
G48584BU
G70101JE
G80920RR
G62765YT
G01768RG
G90659AW
G29545VG
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asymmetric localization of PCP proteins | Homo sapiens |
| Ca2+ pathway | Homo sapiens |
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Class B/2 (Secretin family receptors) | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | Homo sapiens |
| PCP/CE pathway | Homo sapiens |
| TCF dependent signaling in response to WNT | Homo sapiens |
| WNT ligand biogenesis and trafficking | Homo sapiens |
| WNT5:FZD7-mediated leishmania damping | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060766 | autosomal dominant Robinow syndrome 1 |
