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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
caspase 7
Summary
- Gene Symbol
-
- CASP7
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Allosteric enzyme
- Alternative splicing
- Apoptosis
- Cytoplasm
- Nucleus
- Phosphoprotein
- Proteomics identification
- RNA-binding
- Reference proteome
- Secreted
- Thiol protease
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| B4DWA2 |
|
| P55210 |
|
| A0A0A0MRL7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| lymphocyte apoptotic process | ||
| cellular response to staurosporine | ||
| heart development | ||
| fibroblast apoptotic process |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cysteine-type endopeptidase activity | ||
| aspartic-type endopeptidase activity | ||
| peptidase activity | ||
| cysteine-type endopeptidase activity involved in execution phase of apoptosis |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Caspase
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cysteine-type endopeptidase activity |
| hydrolase activity |
| positive regulation of neuron apoptotic process |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1002 | endometritis | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11446 | sciatic neuropathy | |
| DOID:1612 | breast cancer | |
| DOID:219 | colon cancer | |
| DOID:224 | transient cerebral ischemia | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:5199 | ureteral obstruction | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 12369 | MGI:109383 | MOUSE24937 | ||
| 37729 | FB:FBgn0010501 | |||
| 42008 | FB:FBgn0028381 | |||
| 43514 | FB:FBgn0019972 | |||
| 64026 | RGD:620944 | RATNO21206 | ||
| 175007 | WB:WBGene00000819 | |||
| 178272 | WB:WBGene00000417 | |||
| 397819 | Xenbase:XB-GENE-17342236 | |||
| 450745 | 9598_0:002d11 | PANTR01581 | ||
| 486896 | CANLF11486 |
