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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paraoxonase 1
Summary
- Gene Symbol
-
- Pon1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Calcium
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- HDL
- Hydrolase
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P55159 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lactone catabolic process | ||
| response to fatty acid | ||
| response to fluoride |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| spherical high-density lipoprotein particle | ||
| high-density lipoprotein particle | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| phospholipid binding | ||
| arylesterase activity | ||
| acyl-L-homoserine-lactone lactonohydrolase activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- serum paraoxonase/arylesterase 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| acyl-L-homoserine-lactone lactonohydrolase activity |
| aryldialkylphosphatase activity |
| arylesterase activity |
| hydrolase activity |
| metal ion binding |
| response to toxic substance |
| InterPro |
|---|
| Arylesterase |
| Paraoxonase1 |
| Six-bladed beta-propeller, TolB-like |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2355 | anemia | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3393 | coronary artery disease | |
| DOID:3526 | cerebral infarction | |
| DOID:4195 | hyperglycemia | |
| DOID:4448 | macular degeneration | |
| DOID:4481 | allergic rhinitis | |
| DOID:576 | proteinuria | |
| DOID:5844 | myocardial infarction | |
| DOID:684 | hepatocellular carcinoma |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP012808
- Gene Name
- paraoxonase 1
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5444 | HGNC:9204 | |||
| 18979 | 10090_1:001e56 | MGI:103295 | ||
| 171999 | WB:WBGene00017089 | |||
| 172389 | WB:WBGene00003170 | |||
| 187297 | WB:WBGene00010775 | |||
| 335176 | ZFIN:ZDB-GENE-030131-7116 | |||
| 448598 | Xenbase:XB-GENE-491654 | |||
| 4363028 | WB:WBGene00044697 | |||
| 6418581 | WB:WBGene00077701 | |||
| 100721268 | 10141_0:003a43 |
