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Submissions

ectonucleotide pyrophosphatase/phosphodiesterase 2

Summary

Gene Symbol

Enpp2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

84050

PubChem

84050

Alliance of Genome Resources

RGD:69298

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Chemotaxis
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydrolase
Lipid degradation
Metal-binding
Obesity
Reference proteome
Repeat
Secreted
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HRG3
Q64610	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Extracellular lysophospholipase D

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
sphingolipid catabolic process	IEA ISO ISS
positive regulation of substrate adhesion-dependent cell spreading	IDA	22139091
vesicle-mediated transport	IEA
phospholipid metabolic process	ISO
cellular response to cadmium ion	IEP	24361405

GO Hierarchy

biological process

immune system process [inference]

immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

cellular process [inference]

vesicle-mediated transport

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cell motility [inference]

cell migration [inference]

cell chemotaxis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to cadmium ion

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

reproductive process [inference]

multicellular organismal reproductive process [inference]

ovulation cycle [inference]

estrous cycle

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

rhythmic process [inference]

ovulation cycle [inference]

estrous cycle

response to stimulus [inference]

immune response

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

response to polycyclic arene

response to lipid [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

response to inorganic substance [inference]

response to metal ion [inference]

response to cadmium ion [inference]

cellular response to cadmium ion

cellular response to metal ion [inference]

cellular response to cadmium ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to cadmium ion

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to cadmium ion

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

response to oxygen-containing compound [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to cadmium ion

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

regulation of cell motility [inference]

regulation of cell migration

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium morphogenesis

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of lamellipodium morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of lamellipodium morphogenesis [inference]

positive regulation of lamellipodium morphogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of lamellipodium morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

negative regulation of cell-matrix adhesion

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of substrate adhesion-dependent cell spreading

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of substrate adhesion-dependent cell spreading [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of substrate adhesion-dependent cell spreading

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium morphogenesis

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium morphogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of lamellipodium organization [inference]

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium morphogenesis

regulation of lamellipodium morphogenesis [inference]

positive regulation of lamellipodium morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium morphogenesis

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cell-substrate junction organization [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cell motility [inference]

regulation of cell migration

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IBA IDA IEA ISO	12837632 21240271
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

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GO Term	Evidence Code	PMID
scavenger receptor activity	IEA
phosphodiesterase I activity	IBA IMP	17307740
lysophospholipase activity	IBA IDA IEA ISO	12354767 21240271
nucleic acid binding	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds

nuclease activity [inference]

exonuclease activity [inference]

phosphodiesterase I activity

lipase activity [inference]

phospholipase activity [inference]

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

carboxylic ester hydrolase activity [inference]

lysophospholipase activity

binding [inference]

carbohydrate binding [inference]

polysaccharide binding

ion binding [inference]

cation binding [inference]

metal ion binding

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding

cargo receptor activity [inference]

scavenger receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Functional Category

O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

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Gene Ontology
alkylglycerophosphoethanolamine phosphodiesterase activity
calcium ion binding
estrous cycle
hydrolase activity, acting on ester bonds
hydrolase activity
immune response
metal ion binding
phosphatidylcholine catabolic process
phosphodiesterase I activity
scavenger receptor activity

Displaying **all 9** entries
InterPro
Alkaline-phosphatase-like, core domain superfamily
DNA/RNA non-specific endonuclease superfamily
DNA/RNA non-specific endonuclease
Extracellular Endonuclease, subunit A
His-Me finger superfamily
Somatomedin B domain, chordata
Somatomedin B domain
Somatomedin B-like domain superfamily
Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
extracellular space	PMID:12837632

Rhea

RHEA:36203

H₂O + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine

H⁺ + ethanolamine + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate

Enzyme

3.1.4.39

PMID

4855486

RHEA:15965

H₂O + 1-O-alkyl-sn-glycero-3-phosphoethanolamine

H⁺ + ethanolamine + 1-O-alkyl-sn-glycero-3-phosphate

Enzyme

3.1.4.39

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:13207	proliferative diabetic retinopathy	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP012810
Gene Name: ectonucleotide pyrophosphatase/phosphodiesterase 2

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5168		HGNC:3357	HUMAN95310
Mus musculus	18606	10090_1:004881	MGI:1321390	MOUSE16289
Caenorhabditis elegans	179663		WB:WBGene00007753
Caenorhabditis elegans	179665		WB:WBGene00007755
Pan troglodytes	464353			PANTR43174
Canis lupus familiaris	482026			CANLF03176
Sus scrofa	503658			PIGXX22961
Bos taurus	532663			BOVIN06261
Xenopus tropicalis	548690		Xenbase:XB-GENE-1016186
Macaca mulatta	705287			MACMU43255

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements