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fucosyltransferase 10

Summary

Gene Symbol

FUT10

Aliases

alpha (1,3) fucosyltransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

84750

GGDB ID

gg010

HGNC

19234

mRNA

NM_032664

map

8p12

Protein

NP_116053

OMIM

616931

KEGG Gene ID

hsa:84750

PubChem

84750

Alliance of Genome Resources

HGNC:19234

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lysosome
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6P4F1	Fucosyltransferase X Galactoside 3-L-fucosyltransferase 10

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
neuronal stem cell population maintenance	IEA
oligosaccharide biosynthetic process	IEA
neuroblast migration	IEA
nervous system development	NAS	11698403
neuronal stem cell division	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

glycosylation [inference]

fucosylation

N-glycan fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular process [inference]

protein folding

cellular developmental process [inference]

cell development [inference]

hemopoiesis

cell motility [inference]

cell migration [inference]

forebrain cell migration [inference]

telencephalon cell migration [inference]

cerebral cortex cell migration [inference]

cerebral cortex radially oriented cell migration

neuroblast migration

cell division [inference]

stem cell division [inference]

somatic stem cell division [inference]

neuronal stem cell division

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

reproductive process [inference]

fertilization

multicellular organismal process [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis

system development [inference]

nervous system development

cellular developmental process [inference]

cell development [inference]

hemopoiesis

maintenance of cell number [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA
endoplasmic reticulum membrane	IEA
Golgi apparatus	IDA TAS	11698403
Golgi membrane	IEA
lysosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-(1->3)-fucosyltransferase activity	IBA TAS	11698403
fucosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity

alpha-(1->3)-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

GlycoGene Database (GGDB)

GGDB ID

gg010

Gene Symbol

FUT10

Reactions

Displaying **all 5** entries
Donor	Acceptor	Product	Reference
GDP-Fuc	G52934AK	G38753OV	23986452
GDP-Fuc	G25520XG	G95617FJ	23986452
GDP-Fuc	G39213VZ	G64669AQ	19088067
GDP-Fuc	G46055MA	G39775LJ	23986452
GDP-Fuc	G36191CD		19088067

Displaying **all 5** entries
Donor	Acceptor	Product	Reference
GDP-Fuc	G52934AK	G38753OV	23986452
GDP-Fuc	G46055MA	G39775LJ	23986452
GDP-Fuc	G36191CD		19088067
GDP-Fuc	G39213VZ	G64669AQ	19088067
GDP-Fuc	G25520XG	G95617FJ	23986452

Orthologous Gene

Displaying **all 3** entries
Species	Protein	mRNA
Rattus norvegicus	NP_001012360	NM_001012360
Drosophila melanogaster	NP_609288	NM_135444
Mus musculus	AAH62113	BC062113

KEGG BRITE Database

Orthology

K09669

Name

alpha-1,3-fucosyltransferase 10 [EC:2.4.1.-]

References

Disease

Disease Ontology

Displaying entries **1 - 10** of 13 in total

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DO ID	Disease Name	Source
DOID:0060672	Grn-related frontotemporal lobar degeneration with Tdp43 inclusions	DisGeNET
DOID:10914	amnestic disorder	DisGeNET DisGeNET DisGeNET
DOID:11037	dissociative amnesia	DisGeNET
DOID:1324	lung cancer	DisGeNET
DOID:1325	bronchus cancer	DisGeNET
DOID:234	colon adenocarcinoma	DisGeNET
DOID:3571	liver cancer	DisGeNET
DOID:3683	lung benign neoplasm	DisGeNET
DOID:3904	bronchus carcinoma	DisGeNET
DOID:3905	lung carcinoma	DisGeNET DisGeNET

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	34260	FB:FBgn0032117
Latimeria chalumnae	102348890		LATCH00785
Danio rerio	497615	ZFIN:ZDB-GENE-081022-183	DANRE01636
Astyanax mexicanus	103038068		ASTMX10556
Ictalurus punctatus	108277192		ICTPU08793
Salmo trutta	115160079		SALTR69357
Xenopus laevis	414623	Xenbase:XB-GENE-976925
Xenopus tropicalis	444886	Xenbase:XB-GENE-976919
Chrysemys picta bellii	101933727		CHRPI18761
Crocodylus porosus	109323669		CROPO13016

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Other Information

Tools

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Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements