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E3 ubiquitin-protein ligase IRC20

Summary

Gene Symbol

IRC20

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

850949

PubChem

850949

Alliance of Genome Resources

SGD:S000004237

Annotation

Keyword

Acetylation
Helicase
Nucleus
Phosphoprotein
Reference proteome
Stress response
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q06554	Increased recombination centers protein 20

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
DNA repair	IBA
double-strand break repair via nonhomologous end joining	IGI	22367032
double-strand break repair via synthesis-dependent strand annealing	IMP	22367032
double-strand break repair via synthesis-dependent strand annealing	IGI	22367032

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IBA
nucleus	IEA
nucleus	HDA	14562095
mitochondrion	HDA	14576278 16823961

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 10 in total

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Last »
GO Term	Evidence Code	PMID
helicase activity	ISS	10077188
helicase activity	IEA
ubiquitin-protein transferase activity	IDA	24155900
ubiquitin-protein transferase activity	IMP	24155900
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

hydrolase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

ATP-dependent chromatin remodeler activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity

ATP-dependent activity, acting on DNA

ATP-dependent chromatin remodeler activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

helicase

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
hydrolase activity
metal ion binding
nucleotide binding
protein polyubiquitination

Displaying **all 9** entries
InterPro
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
P-loop containing nucleoside triphosphate hydrolase
SNF2, N-terminal
SNF2-like, N-terminal domain superfamily
SNF2/RAD5-like, C-terminal helicase domain
Zinc finger, RING-type, conserved site
Zinc finger, RING-type
Zinc finger, RING/FYVE/PHD-type

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
mitochondrion	PMID:14576278 PMID:16823961
nucleus	PMID:14562095

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	850949	Xenbase:XB-GENE-959908

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LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements