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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sphinganine-1-phosphate aldolase DPL1
Summary
- Gene Symbol
-
- DPL1
- Organism
- Saccharomyces cerevisiae S288C
Annotation
- Keyword
-
- 3D-structure
- Endoplasmic reticulum
- Glycoprotein
- Lyase
- Pyridoxal phosphate
- Reference proteome
- Sphingolipid metabolism
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q05567 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| carboxylic acid metabolic process | ||
| calcium-mediated signaling | ||
| sphingolipid catabolic process | ||
| cellular response to starvation | ||
| sphingolipid metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| peroxisome | ||
| cortical endoplasmic reticulum | ||
| perinuclear endoplasmic reticulum | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lyase activity | ||
| carbon-carbon lyase activity | ||
| sphinganine-1-phosphate aldolase activity | ||
| identical protein binding |
|
|
| pyridoxal phosphate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Sphingosine-1-phosphate lyase
- Functional Category
-
- E: Amino acid transport and metabolism
- H: Coenzyme transport and metabolism
- J: Translation, ribosomal structure and biogenesis
| Gene Ontology |
|---|
| aspartate 1-decarboxylase activity |
| carbon-carbon lyase activity |
| carboxylic acid metabolic process |
| lyase activity |
| pyridoxal phosphate binding |
| sphingolipid catabolic process |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080265 | nephrotic syndrome type 14 | |
| DOID:10595 | Charcot-Marie-Tooth disease | |
| DOID:1184 | nephrotic syndrome | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 8879 | HGNC:10817 | |||
| 20397 | MGI:1261415 | |||
| 46059 | FB:FBgn0010591 | |||
| 176857 | WB:WBGene00004981 | |||
| 181859 | WB:WBGene00006418 | |||
| 190868 | WB:WBGene00022427 | |||
| 286896 | RGD:628599 | |||
| 2891993 | 28985_0:0004d0 | |||
| 5545934 | 436907_0:000d26 | |||
| 8206544 | 4956_0:0013f3 |
