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histone-binding protein SET3

Summary

Gene Symbol

SET3

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853900

PubChem

853900

Alliance of Genome Resources

SGD:S000001737

Annotation

Keyword

3D-structure
Activator
Chromatin regulator
Meiosis
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
P36124

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein methylation	IMP	31960028
chromatin organization	IEA
regulation of DNA-templated transcription	IBA IMP	19379692
regulation of transcription, DNA-templated	IBA IMP	19379692
DNA damage response

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

methylation [inference]

macromolecule methylation [inference]

protein methylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

macromolecule modification [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

macromolecule methylation [inference]

protein methylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

cellular process [inference]

cell cycle [inference]

meiotic cell cycle

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization

chromatin remodeling [inference]

transcription initiation-coupled chromatin remodeling

reproductive process [inference]

meiotic cell cycle

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

regulation of nuclear division [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Set3 complex	IBA IDA	11711434
Rpd3L-Expanded complex	HDA IBA	19040720
nucleus

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

histone deacetylase complex [inference]

catalytic complex [inference]

histone deacetylase complex [inference]

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
zinc ion binding	RCA	30358795
metal ion binding	IEA
methylated histone binding	IBA IDA	17142463

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

histone binding [inference]

methylated histone binding

modification-dependent protein binding [inference]

methylation-dependent protein binding [inference]

methylated histone binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ankyrin

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
Set3 complex	PMID:11711434
Rpd3L-Expanded complex	PMID:19040720

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0070053	autosomal dominant intellectual developmental disorder 23	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:3748	esophagus squamous cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 34 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	39551		FB:FBgn0036398
Homo sapiens	55209		HGNC:25566
Mus musculus	72895		MGI:1920145
Rattus norvegicus	297514		RGD:1310433
Danio rerio	570278		ZFIN:ZDB-GENE-080523-1
Xenopus tropicalis	779539		Xenbase:XB-GENE-976589
Kluyveromyces lactis	2895775	28985_0:001142
Eremothecium gossypii ATCC 10895	4621866	284811_0:000f3e
Vanderwaltozyma polyspora DSM 70294	5543546	436907_0:00048f
Vanderwaltozyma polyspora DSM 70294	5544196	436907_0:0006f8