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Guidelines

MIRAGE

Atg2p

Summary

Gene Symbol

ATG2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

855479

PubChem

855479

Alliance of Genome Resources

SGD:S000005186

Annotation

Keyword

Autophagy
Coiled coil
Endoplasmic reticulum
Lipid transport
Membrane
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P53855	Sporulation-specific protein 72

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
autophagosome assembly	IMP	11382761
autophagosome assembly	IBA
autophagy of mitochondrion	IMP	19793921
autophagy of mitochondrion	IBA
pexophagy	IDA	11382760

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy of mitochondrion

pexophagy

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

autophagy of peroxisome [inference]

pexophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy of mitochondrion

pexophagy

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

autophagy of peroxisome [inference]

pexophagy

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy of mitochondrion

pexophagy

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

autophagy of peroxisome [inference]

pexophagy

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

process utilizing autophagic mechanism [inference]

autophagy of mitochondrion

pexophagy

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

autophagy of peroxisome [inference]

pexophagy

cytoplasm to vacuole transport by the Cvt pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

organelle disassembly [inference]

cellular component disassembly [inference]

organelle disassembly [inference]

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

membrane organization [inference]

intermembrane lipid transfer

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

intermembrane lipid transfer

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
phagophore assembly site	IDA	11689437 18497569
phagophore assembly site	IBA
cytoplasm	IDA	11382760
cytoplasm	HDA	22842922
endoplasmic reticulum	IEA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

phagophore assembly site membrane

extrinsic component of membrane [inference]

extrinsic component of organelle membrane [inference]

extrinsic component of phagophore assembly site membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

phagophore

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phosphatidylinositol-3-phosphate binding	IDA	27498190
phosphatidylinositol-3-phosphate binding	IBA
protein-membrane adaptor activity	IBA
lipid transfer activity

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

lipid transfer activity

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-3-phosphate binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

protein-membrane adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

autophagy-related protein

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
autophagosome assembly
lipid transport
phosphatidylinositol-3-phosphate binding
piecemeal microautophagy of the nucleus

Displaying **all 4** entries
InterPro
Atg2, N-terminal domain
Atg2/VPS13, C-terminal
Autophagy-related protein 2, middle RBG module
Autophagy-related protein 2

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
phagophore assembly site	PMID:11689437 PMID:18497569
phagophore	PMID:23549786
cytosol	PMID:26928762
cytoplasm	PMID:11382760 PMID:22842922

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	23130	Xenbase:XB-GENE-5818802
Xenopus tropicalis	55102	Xenbase:XB-GENE-5763717
Xenopus tropicalis	180949	Xenbase:XB-GENE-5818802
Xenopus tropicalis	855479	Xenbase:XB-GENE-5763717

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025