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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
tankyrase
Summary
- Gene Symbol
-
- TNKS
- Aliases
-
- ARTD5
- PARP-5a
- PARP5A
- TIN1
- TINF1
- TNKS1
- TRF1-interacting ankyrin-related ADP-ribose polymerase 1
- pART5
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- ANK repeat
- Alternative splicing
- Cytoskeleton
- Glycosyltransferase
- Golgi apparatus
- Membrane
- Metal-binding
- Mitosis
- NAD
- Nuclear pore complex
- Nucleotidyltransferase
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Telomere
- Ubl conjugation
- Wnt signaling pathway
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| peptidyl-threonine phosphorylation | ||
| protein poly-ADP-ribosylation | ||
| spindle assembly | ||
| positive regulation of telomere maintenance via telomerase | ||
| positive regulation of transcription by RNA polymerase II |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of organelle organization [inference]
negative regulation of cellular component organization [inference]
regulation of cell cycle [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| NAD+ ADP-ribosyltransferase activity | ||
| zinc ion binding | ||
| histone binding | ||
| NAD+-protein ADP-ribosyltransferase activity | ||
| nucleotidyltransferase activity |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050424 | familial adenomatous polyposis | |
| DOID:0050569 | Seckel syndrome | |
| DOID:0050789 | tarsal-carpal coalition syndrome | |
| DOID:0050902 | medulloblastoma | |
| DOID:0060254 | Robinow syndrome | |
| DOID:0060578 | Noonan syndrome 1 | |
| DOID:0060580 | Noonan syndrome 2 | |
| DOID:0060581 | Noonan syndrome 3 | |
| DOID:0060582 | Noonan syndrome 4 | |
| DOID:0060583 | Noonan syndrome 5 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 43095 | FB:FBgn0027508 | ||
| 103177658 | CALMI13525 | ||
| 102360174 | LATCH05319 | ||
| 559022 | ZFIN:ZDB-GENE-030131-7450 | ||
| 567533 | ZFIN:ZDB-GENE-030131-4865 | ||
| 113589036 | ELEEL42621 | ||
| 495279 | Xenbase:XB-GENE-17332882 | ||
| 549762 | Xenbase:XB-GENE-968819 | ||
| 100497226 | Xenbase:XB-GENE-5828012 | ||
| 101947766 | CHRPI23265 |
