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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
insulin receptor substrate 2
Summary
- Gene Symbol
-
- IRS2
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of glucose import | ||
| mammary gland development | ||
| brain development | ||
| positive regulation of mesenchymal cell proliferation | ||
| cellular response to peptide |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| 14-3-3 protein binding | ||
| phosphatidylinositol 3-kinase binding | ||
| phosphatidylinositol 3-kinase activator activity | ||
| protein binding | ||
| transmembrane receptor protein tyrosine kinase adaptor activity |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:1059 | intellectual disability | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10914 | amnestic disorder | |
| DOID:11476 | osteoporosis | |
| DOID:4194 | glucose metabolism disease | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 64880 | FB:FBgn0024248 | ||
| 102364884 | LATCH12871 | ||
| 393285 | ZFIN:ZDB-GENE-040426-975 | ||
| 572001 | ZFIN:ZDB-GENE-081104-462 | ||
| 103034135 | ASTMX00180 | ||
| 108266735 | ICTPU31242 | ||
| 106582130 | SALSA100383 | ||
| 115155832 | SALTR09752 | ||
| 115161187 | SALTR14739 | ||
| 101162408 | ORYLA09987 |
