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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase domain 15
Summary
- Gene Symbol
-
- ADAM15
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Angiogenesis
- Cell adhesion
- Cell junction
- Cleavage on pair of basic residues
- Collagen degradation
- Cytoplasmic vesicle
- Disulfide bond
- EGF-like domain
- Flagellum
- Glycoprotein
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- SH3-binding
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q13444 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell-matrix adhesion | ||
| proteolysis | ||
| cardiac epithelial to mesenchymal transition | ||
| negative regulation of cell growth | ||
| immune response to tumor cell |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| integrin binding | ||
| SH3 domain binding | ||
| immunoglobulin receptor binding | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Disintegrin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| ADAM, cysteine-rich domain |
| Disintegrin domain superfamily |
| Disintegrin domain |
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12B, ADAM/reprolysin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1793 | pancreatic cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11490 | MGI:1333882 | MOUSE38786 | ||
| 57025 | RGD:620402 | RATNO23787 | ||
| 181489 | WB:WBGene00000074 | |||
| 457354 | 9598_0:000371 | PANTR22451 | ||
| 490434 | CANLF17443 | |||
| 719030 | MACMU23204 | |||
| 795199 | ZFIN:ZDB-GENE-070809-4 | |||
| 3772109 | FB:FBgn0265140 | |||
| 100021565 | MONDO12026 | |||
| 100145641 | Xenbase:XB-GENE-5944438 |
