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acyl-CoA binding domain containing 5

Summary

Gene Symbol

ACBD5

Organism

Homo sapiens (human)

External Links

NCBI Gene

91452

PubChem

91452

Alliance of Genome Resources

HGNC:23338

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Autophagy
Coiled coil
Leukodystrophy
Lipid-binding
Peroxisome
Phosphoprotein
Proteomics identification
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying **all 5** entries
UniProt	Protein Name
B7Z2A7
B7Z2R7
Q5T8D3
B7Z9D0
Q8NCM9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fatty acid metabolic process	IBA
pexophagy	IMP	24535825

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

pexophagy

autophagy of peroxisome [inference]

pexophagy

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

pexophagy

autophagy of peroxisome [inference]

pexophagy

cellular lipid metabolic process [inference]

fatty acid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

pexophagy

autophagy of peroxisome [inference]

pexophagy

cellular lipid metabolic process [inference]

fatty acid metabolic process

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

pexophagy

autophagy of peroxisome [inference]

pexophagy

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	HDA	19946888
peroxisome	IBA IDA	24535825
nucleoplasm	IDA
peroxisomal membrane	TAS
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
fatty-acyl-CoA binding	IBA
molecular_function	ND

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

fatty acid derivative binding [inference]

fatty-acyl-CoA binding

amide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ion binding [inference]

anion binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

sulfur compound binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

acyl-CoA-binding domain-containing protein

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080946	retinal dystrophy with leukodystrophy	Alliance of Genome Resources
DOID:906	peroxisomal disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 84 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	33492		FB:FBgn0031478
Mus musculus	74159		MGI:1921409	MOUSE33321
Rattus norvegicus	307170		RGD:1309411	RATNO12950
Bos taurus	353160			BOVIN04330
Xenopus laevis	447727		Xenbase:XB-GENE-982916
Pan troglodytes	450368	9598_0:002cde		PANTR00360
Canis lupus familiaris	477987			CANLF06463
Xenopus tropicalis	493542		Xenbase:XB-GENE-982910
Danio rerio	553674		ZFIN:ZDB-GENE-050522-268	DANRE26126
Rattus norvegicus	679565			RATNO33936

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024