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MIRAGE
lipopolysaccharide induced TNF factor
Summary
- Gene Symbol
-
- LITAF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Charcot-Marie-Tooth disease
- Cytoplasm
- DNA-binding
- Disease variant
- Endosome
- Golgi apparatus
- Lysosome
- Metal-binding
- Neurodegeneration
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transcription regulation
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| Q99732 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cytokine production | ||
| regulation of macrophage cytokine production | ||
| positive regulation of canonical NF-kappaB signal transduction | ||
| positive regulation of transcription by RNA polymerase II | ||
| cellular response to lipopolysaccharide |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| nucleus | ||
| nucleoplasm | ||
| lysosomal membrane | ||
| Golgi apparatus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA-binding transcription activator activity, RNA polymerase II-specific | ||
| protein binding | ||
| zinc ion binding | ||
| zinc ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- lipopolysaccharide-induced tumor necrosis factor-alpha factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| zinc ion binding |
| InterPro |
|---|
| LITAF domain containing protein |
| LPS-induced tumour necrosis factor alpha factor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110151 | Charcot-Marie-Tooth disease type 1C |
