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Lipopolysaccharide-induced tumor necrosis factor-alpha factor

Summary

UniProt ID

Q99732

Gene Symbol

LITAF
PIG7
SIMPLE

Gene ID

9516

Organism

Homo sapiens (human)

External Links

GlyGen: Q99732
PubChem: Q99732
RaftProt: Q99732
Re-Glyco: Q99732

Annotation

Keyword

Alternative splicing
Cell membrane
Charcot-Marie-Tooth disease
Cytoplasm
DNA-binding
Disease variant
Endosome
Golgi apparatus
Lysosome
Metal-binding
Neurodegeneration
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Transcription regulation
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
nucleus
plasma membrane
intracellular membrane-bounded organelle
Golgi membrane
nucleoplasm
Golgi apparatus
lysosomal membrane
cytoplasmic side of plasma membrane
cytoplasmic side of late endosome membrane
cytoplasmic side of early endosome membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
cellular response to lipopolysaccharide
negative regulation of non-canonical NF-kappaB signal transduction
positive regulation of canonical NF-kappaB signal transduction
regulation of macrophage cytokine production
regulation of cytokine production
positive regulation of transcription by RNA polymerase II

Displaying **all 5** entries
GO Term
zinc ion binding
WW domain binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
identical protein binding

Annotation information from UniProt.

Sequence

MSVPGPYQAATGPSSAPSAPPSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPNNNPITVQTVYVQHPITFLDRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIAGCCFIPFCVDALQDVDHYCPNCRALLGTYKRL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites