G00058MO

Summary
GlyTouCan ID
G00058MO
IUPAC Condensed
Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-
Motifs
I' antigen Type 2 LN2
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
748.27
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G00058MO
Displaying 1 entry
Archetype α β
G14052TA
G00721IC
G00058MO
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
FUT4 GDP-Fuc
G00058MO
R
G63021RS
R
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
FUT4 GDP-Fuc
G00058MO
R
G63021RS
R
GCNT2 UDP-GlcNAc
G00058MO
R
G80198LX
R
B3GNT5 UDP-GlcNAc
G00058MO
2AB
G73480MV
2AB
B3GNT2 UDP-GlcNAc
G00058MO
2AB
G73480MV
2AB
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
B3GNT4 UDP-GlcNAc
G00058MO
2AB
GlycoEpitope
Epitope ID
EP0139
Epitope Name
i Antigen
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:b-dglc-HEX-1:5
5s:n-acetyl
6b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3o(3+1)4d
4:4d(2+1)5n
5:4o(4+1)6d
WURCS
WURCS=2.0/2,4,3/[a2122h-1b_1-5_2*NCC/3=O][a2112h-1b_1-5]/1-2-1-2/a4-b1_b3-c1_c4-d1
Literature
Displaying entries 1 - 10 of 23 in total
PubMed ID Title First Author Publication Date Source
18977853 Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain Nagae M 2008 Oct 24
  • PubChem
16990264 Crystal Structure of the Galectin-9 N-terminal Carbohydrate Recognition Domain from Mus musculus Reveals the Basic Mechanism of Carbohydrate Recognition Nagae M 2006 Nov 24
  • PubChem
12424189 The molecular genetics of the human I locus and molecular background explain the partial association of the adult i phenotype with congenital cataracts Yu LC 2003 Mar 15
  • PubChem
11283017 Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids Togayachi A 2001 Jun 22
  • PubChem
11356829 A novel human Gal-3-O-sulfotransferase: molecular cloning, characterization, and its implications in biosynthesis of (SO(4)-3)Galbeta1-4(Fucalpha1-3)GlcNAc El-Fasakhany FM 2001 Jul 20
  • PubChem
10642612 Sulfation of sialyl N-acetyllactosamine oligosaccharides and fetuin oligosaccharides by keratan sulfate Gal-6-sulfotransferase Torii T 2000 Feb 01
  • PubChem
10622713 Alpha1,3-fucosyltransferase 9 (FUT9; Fuc-TIX) preferentially fucosylates the distal GlcNAc residue of polylactosamine chain while the other four alpha1,3FUT members preferentially fucosylate the inner GlcNAc residue Nishihara S 1999 Nov 30
  • PubChem
10092606 Regulation of I-branched poly-N-acetyllactosamine synthesis. Concerted actions by I-extension enzyme, I-branching enzyme, and beta1,4-galactosyltransferase I Ujita M 1999 Apr 02
  • PubChem
9147050 Sulfation of sialyl lactosamine oligosaccharides by chondroitin 6-sulfotransferase Habuchi O 1997 Apr
  • PubChem
7590936 Production of human monoclonal antibodies to i blood group by EBV-induced transformation: possible presence of a new glycolipid in cord red cell membranes and human hematopoietic cell lines Nagatsuka Y 1995 May
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying all 5 entries
Title Authors Source Publication Date PubMed ID
Sialyltransferases of marine bacteria efficiently utilize glycosphingolipid substrates.
  • Kushi Y
  • Kamimiya H
  • Hiratsuka H
  • Nozaki H
  • Fukui H
  • Yanagida M
  • Hashimoto M
  • Nakamura K
  • Watarai S
  • Kasama T
  • Kajiwara H
  • Yamamoto T
Glycobiology 2010 Feb 19837852
Expression of the large I antigen forming beta-1,6-N-acetylglucosaminyltransferase in various tissues of adult mice.
  • Magnet AD
  • Fukuda M
Glycobiology 1997 Mar 9134435
Further definition of the size of the blood group-i antigenic determinant using a chemically synthesised octasaccharide of poly-N-acetyllactosamine type.
  • Feizi T
  • Hounsell EF
  • Alais J
  • Veyrières A
  • David S
Carbohydr Res 1992 Apr 10 1381279
Monoclonal antibody specific for lactosylceramide.
  • Symington FW
  • Bernstein ID
  • Hakomori S
J Biol Chem 1984 May 10 6585365
Association of hemoglobin Saint Etienne (alpha2beta295F8 His replaced by G1n) with hemoglobins A and F. Synthesis and subunit exchange in vitro.
  • Godeau JF
  • Beuzard YG
  • Cacheleux J
  • Brizard CP
  • Gibaud A
  • Rosa J
J Biol Chem 1976 Jul 25 932034

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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