G00672PE

Summary
GlyTouCan ID
G00672PE
IUPAC Condensed
Neu5Ac(a2-3)Gal6S(b1-4)[Fuc(a1-3)]GlcNAc(b1-
Motifs
6O-Sulfo-sialyl Lewis x 6O-sulfo SLex
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
900.25
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
47487
GlycoEpitope
Epitope ID
EP0014
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:a-lgal-HEX-1:5|6:d
4b:b-dgal-HEX-1:5
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
7s:sulfate
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d
4:4o(3+2)5d
5:5d(5+1)6n
6:4o(6+1)7n
WURCS
WURCS=2.0/4,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5_6*OSO/3=O/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-4/a3-b1_a4-c1_c3-d2
Literature
Displaying entries 1 - 10 of 27 in total
PubMed ID Title First Author Publication Date Source
27357658 Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8 Pröpster JM 2016 Jun 29
  • PubChem
14593101 Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing Hiraoka N 2004 Jan 23
  • GlyGen
  • GlycoEpitope
15175329 N-Acetylglucosamine 6-O-Sulfotransferase-1 Regulates Expression of L-Selectin Ligands and Lymphocyte Homing Uchimura K 2004 Aug 13
  • GlyGen
  • GlycoEpitope
14568956 Complement regulatory protein C1 inhibitor binds to selectins and interferes with endothelial-leukocyte adhesion Cai S 2003 Nov 01
  • GlyGen
  • GlycoEpitope
12889478 Endoglycan, a Member of the CD34 Family, Functions as an L-selectin Ligand through Modification with Tyrosine Sulfation and Sialyl Lewis x Fieger CB 2003 Jul 25
  • GlyGen
  • GlycoEpitope
12385579 Increased expression of sialyl Lewis(x) antigen in penetrating growth type A early gastric cancer Nakagoe T 2002 Sep
  • GlyGen
  • GlycoEpitope
11919403 High Endothelial Venule-Like Vessels in the Interstitial Lesions of Human Glomerulonephritis Takaeda M 2002 Jan
  • GlyGen
  • GlycoEpitope
12163379 Glycosylation might provide endothelial zip codes for organ-specific leukocyte traffic into inflammatory sites Renkonen J 2002 Aug
  • GlyGen
  • GlycoEpitope
11520459 Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes Hemmerich S 2001 Aug
  • GlyGen
  • GlycoEpitope
10528213 L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1 Tu L 1999 Nov 01
  • GlyGen
  • GlycoEpitope

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025