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glucosaminyl (N-acetyl) transferase 1, core 2

Summary

Gene Symbol

Gcnt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14537

KEGG Gene ID

mmu:14537

PubChem

14537

Alliance of Genome Resources

MGI:95676

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Nucleotide-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q09324	Core 2 beta-1,6-N-acetylglucosaminyltransferase Core 2-branching enzyme Core2-GlcNAc-transferase Leukocyte type core 2 beta-1,6-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
leukocyte tethering or rolling	ISO ISS
cell adhesion molecule production	ISO ISS
response to insulin	IEA
O-glycan processing, core 2	IMP ISO ISS	9881978
kidney morphogenesis	IGI	19349303

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

cell adhesion molecule production

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

kidney morphogenesis

tissue morphogenesis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

Displaying **all 4** entries
GO Term	Evidence Code	PMID
Golgi cisterna	ISO ISS
trans-Golgi network	IEA ISO
Golgi membrane	IEA
extracellular space	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IBA IDA ISO	12954635 22056345
nucleotide binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 14

KEGG BRITE Database

Orthology

K00727

Name

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]

References

1329093

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05910	2.4.1.102 2.4.1.148	G57321FI	G00041MO
R05912	2.4.1.102	G00031MO	G00033MO

Rhea

RHEA:56212

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

RHEA:56216

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

Ortholog

Displaying entries **1 - 10** of **105** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2650		HGNC:4203	HUMAN97323
Rattus norvegicus	64043	10116_1:00061a	RGD:621370	RATNO20661
Caenorhabditis elegans	172446		WB:WBGene00001643
Caenorhabditis elegans	172447		WB:WBGene00001644
Caenorhabditis elegans	173108		WB:WBGene00001642
Caenorhabditis elegans	173109		WB:WBGene00001641
Caenorhabditis elegans	173114		WB:WBGene00001640
Caenorhabditis elegans	174679		WB:WBGene00001626
Bos taurus	281778			BOVIN34476
Pan troglodytes	472959			PANTR44141