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core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1

Summary

Gene Symbol

C1galt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

94192

KEGG Gene ID

mmu:94192

PubChem

94192

Alliance of Genome Resources

MGI:2151071

Annotation

Keyword

Angiogenesis
Developmental protein
Differentiation
Disulfide bond
Glycosyltransferase
Manganese
Metal-binding
Nucleotide-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JJ06	Core 1 O-glycan T-synthase Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 Core 1 beta1,3-galactosyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
O-glycan processing, core 1	ISO	11677243
protein O-linked glycosylation	IMP	21383503
intestinal epithelial cell development	IMP	21383503
kidney development	IEA ISO
angiogenesis	IMP ISO	14745002

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

animal organ development [inference]

kidney development

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IBA IEA ISO
metal ion binding	IEA
nucleotide binding	IEA
galactosyltransferase activity	ISO	11677243

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

galactosyltransferase activity

beta-1,3-galactosyltransferase activity [inference]

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Functional Category

F: Nucleotide transport and metabolism
I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 3** entries
Gene Ontology
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity
metal ion binding
transferase activity

Displaying **all 2** entries
InterPro
C1GALT1/C1GALT1-specific chaperone 1
Fringe-like, glycosyltransferase domain

KEGG BRITE Database

Orthology

K00731

Name

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]

References

11677243

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO

Rhea

RHEA:15621

an N-acetyl-α-D-galactosaminyl derivative + UDP-α-D-galactose

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.122

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060050	autoimmune disease of blood	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **116** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	32896		FB:FBgn0030984
Drosophila melanogaster	33482		FB:FBgn0031469
Drosophila melanogaster	33485		FB:FBgn0031472
Drosophila melanogaster	34215		FB:FBgn0032078
Drosophila melanogaster	35792		FB:FBgn0033271
Homo sapiens	56913		HGNC:24337	HUMAN87827
Rattus norvegicus	65044	10116_1:00193e	RGD:621105	RATNO29866
Caenorhabditis elegans	176455		WB:WBGene00008019
Danio rerio	337131		ZFIN:ZDB-GENE-030131-9075
Pan troglodytes	472288			PANTR39692

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements