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Activating molecule in BECN1-regulated autophagy protein 1

Summary

UniProt ID

A2AH22

Gene Symbol

Ambra1
Kiaa1736

Organism

Mus musculus (house mouse)

External Links

GlyGen: A2AH22
PubChem: A2AH22
The O-GlcNAc Database: A2AH22
O-GlcNAcAtlas: A2AH22

Annotation

Keyword

Alternative splicing
Autophagy
Cell cycle
Cell junction
Cytoplasmic vesicle
Cytoskeleton
Developmental protein
Differentiation
Endoplasmic reticulum
Isopeptide bond
Methylation
Mitochondrion
Neurogenesis
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
Ubl conjugation pathway
WD repeat

Gene Ontology (GO)

Displaying entries **11 - 20** of 20 in total

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2
GO Term
negative regulation of cardiac muscle cell apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of neuron apoptotic process
positive regulation of regulatory T cell differentiation
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of protein dephosphorylation
response to mitochondrial depolarisation
positive regulation of mitophagy
positive regulation of free ubiquitin chain polymerization
regulation of G1/S transition of mitotic cell cycle

Displaying entries **1 - 10** of 11 in total

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GO Term
phagocytic vesicle
axoneme
Cul4-RING E3 ubiquitin ligase complex
endoplasmic reticulum
cytosol
nucleus
cytoplasm
mitochondrion
intracellular membrane-bounded organelle
autophagosome

Displaying **all 4** entries
GO Term
GTPase binding
ubiquitin ligase-substrate adaptor activity
protein phosphatase binding
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTTVECCQHPGILCLCSRCAGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTRTVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVSTTFEGMPPSGNQLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEEPGAASSGPGEGEGSEYGGSGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELPQPALSSSSPVPIPVPLASNEGPTMHCNVTNNSHLPEGDGSNRGEAAGPSGEPQNR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites