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Activating molecule in BECN1-regulated autophagy protein 1

Summary

UniProt ID

A2AH22

Gene Symbol

Ambra1
Kiaa1736

Organism

Mus musculus (house mouse)

External Links

GlyGen: A2AH22
PubChem: A2AH22
The O-GlcNAc Database: A2AH22
O-GlcNAcAtlas: A2AH22

Annotation

Keyword

Alternative splicing
Autophagy
Cell cycle
Cell junction
Cytoplasmic vesicle
Cytoskeleton
Developmental protein
Differentiation
Endoplasmic reticulum
Isopeptide bond
Methylation
Mitochondrion
Neurogenesis
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
Ubl conjugation pathway
WD repeat

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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2

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GO Term
negative regulation of neuron apoptotic process
positive regulation of regulatory T cell differentiation
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of protein dephosphorylation
response to mitochondrial depolarisation
positive regulation of autophagy
negative regulation of cell population proliferation
neural tube development
cell differentiation
autophagosome assembly

Displaying entry **11 - 11** of 11 in total

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1

2
GO Term
focal adhesion

Displaying **all 4** entries
GO Term
GTPase binding
ubiquitin ligase-substrate adaptor activity
protein phosphatase binding
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTTVECCQHPGILCLCSRCAGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTRTVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVSTTFEGMPPSGNQLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEEPGAASSGPGEGEGSEYGGSGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELPQPALSSSSPVPIPVPLASNEGPTMHCNVTNNSHLPEGDGSNRGEAAGPSGEPQNR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites