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Rho guanine nucleotide exchange factor 5

Summary

UniProt ID

E9Q7D5

Gene Symbol

Arhgef5

Gene ID

54324

Organism

Mus musculus (house mouse)

External Links

GlyGen: E9Q7D5
The O-GlcNAc Database: E9Q7D5
O-GlcNAcAtlas: E9Q7D5
Re-Glyco: E9Q7D5

Annotation

Keyword

Cell junction
Cell projection
Cytoplasm
Guanine-nucleotide releasing factor
Lipid-binding
Nucleus
Phosphoprotein
Reference proteome
SH3 domain

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
plasma membrane
cell projection
anchoring junction
nucleoplasm
cytosol
podosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
positive regulation of JUN kinase activity
positive regulation of stress fiber assembly
hematopoietic stem cell homeostasis
myeloid dendritic cell chemotaxis
positive regulation of DNA-binding transcription factor activity
positive regulation of podosome assembly
positive regulation of protein import
intracellular signal transduction
actin cytoskeleton organization

Displaying **all 2** entries
GO Term
guanyl-nucleotide exchange factor activity
lipid binding

Annotation information from UniProt.

Sequence

MEAEEPEYGVSTEVPDIEELKTIPEGIMRSSQIPALDPEAQEDRDPSYKWTDGHRPVMNQSKVLRDMGDHTPNSMAIFFKKESSDMETSQEILLAEACNTPDQQEAVIQSLKDRLSRTIAAPELLACAVQEEWLDIPSKLDNRVGAELQSELMSLTLAVSKEKEEEETSPDTSIPRGSWPPCKTHPGETEQTQGSGSELLRQGKQLQLEATQENQGQEGFLQSQEAQGLEEQEGQEVEIQEEGTLNEGICFGGLLGEQEEVEEGFNGNEEEQKQGQIQSYMLLGGQWENEGLSGELEGLNYSERGQENRERRVWVLRDSEEEGQDQESREVEERRVATQYTENQRLVEKSEIVKRKQRDHDQTGKVMPVRDQKEVVDSGDRVQGNGDSGGQTAVEGSRPGEDSKPSLPVASVDPEVLSPGTLFPGISSSVADIPQIQKEPVCEELSPQAPALEPTEWSHQPISPPASFAPEESLDNRTHNSQQEEFRLRKGIEVVSASTSVAPSGTRDSPPFSPPNVFSSTATLSPVSSSVILPEETPTASASADTPHHCGPCETPPLPAKSSRYPCATSDTANPHSPLSSYTGVTQHLRSNSFPGSHRTEQTPDSLGMSLSFSHLELPQRPPKPAIYGSLTPRRNRRSRDGIVFSDSSTALFALKQDSEEFTSNPERPSSPHGSPTWGSPQNSAFAIGSPANVSSPPTVSMDMTIREALLPIPPEKRHSYSHIVERDGLLHEVASTLKRHSHPPPLTLSSGLHRSSKGSFSLVPDSTVARQHRPLPSTPESPNHTQTSIPSRLRYNKPLPPTPDMPEFYHPSISSSYISRMYRPLPPVPIIDPSSEPPPLPPKSRGRSKSIQGGVIHSGGQAKPRPNNQDWTASTLSVGRTSWPPATGRSTESLPLTSRCNNEVSPGLAFSNMTNLLSPSSPTTPWIPDLQRPTTKDESGLTEESEPPVRGSFRRSAPQEEFNNTRRSALGSRKNSEKPLHHQLEKASSWPHRRDPARTSESSSEQVVLGQVPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLISSQLLYQEYSDVVLNKEIQSQQRLDSLAEPHGLSSPRHRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSAQLRGTLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLNHAADFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPICQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLRRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLLHNAQGTQVEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	GlyTouCan ID	Source
496	G49108TO	GlyGen
500	G49108TO	GlyGen The O-GlcNAc Database
784	G36379GD	GlyGen
803		GlyGen
859	G49108TO	The O-GlcNAc Database
899	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
CDC42 GTPase cycle	Mus musculus
G alpha (12/13) signalling events	Mus musculus
NRAGE signals death through JNK	Mus musculus
RAC1 GTPase cycle	Mus musculus
RHOA GTPase cycle	Mus musculus
RHOB GTPase cycle	Mus musculus
RHOC GTPase cycle	Mus musculus
RHOG GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements