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Dihydrolipoyl dehydrogenase, mitochondrial

Summary

UniProt ID

O08749

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlyGen: O08749
PubChem: O08749
The O-GlcNAc Database: O08749
RaftProt: O08749

Annotation

Keyword

Acetylation
Cytoplasmic vesicle
Direct protein sequencing
Disulfide bond
FAD
Flagellum
Mitochondrion
NAD
Nucleus
Oxidoreductase
Phosphoprotein
Redox-active center
Reference proteome
Transit peptide

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
acetyl-CoA biosynthetic process from pyruvate
2-oxoglutarate metabolic process
mitochondrial electron transport, NADH to ubiquinone
branched-chain amino acid catabolic process
proteolysis
gastrulation
regulation of membrane potential
sperm capacitation
lipoate metabolic process
dihydrolipoamide metabolic process

Displaying **all 10** entries
GO Term
acetyltransferase complex
nucleus
mitochondrion
mitochondrial matrix
cilium
motile cilium
myelin sheath
oxoglutarate dehydrogenase complex
pyruvate dehydrogenase complex
acrosomal matrix

Displaying **all 6** entries
GO Term
flavin adenine dinucleotide binding
NAD binding
dihydrolipoyl dehydrogenase activity
pyruvate dehydrogenase (NAD+) activity
lipoamide binding
2-oxoisovalerate dehydrogenase (acylating) activity

Annotation information from UniProt.

Sequence

MQSWSRVYRSLAKKGHFNRISHGLQGVSSVPLRTYADQPIEADVTVIGSGPGGYVAAIKSAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEIPEVRLNLEKMMEQKHSAVKALTGGIAHLFKQNKVVHVNGFGKITGKNQVTATKADGSTQVIDTKNILVATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKLVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQRQGFKFKLNTKVTGATKKSDGKIDVSVEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPKGRIPVNNRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEFKIGKFPFAANSRAKTNADTDGMVKILGHKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAAAFGKPINF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
73			G05049YU	GlyGen
157			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV	Mus musculus
Branched-chain amino acid catabolism	Mus musculus
Glycine degradation	Mus musculus
Mitochondrial protein degradation	Mus musculus
OADH complex synthesizes glutaryl-CoA from 2-OA	Mus musculus
PDH complex synthesizes acetyl-CoA from PYR	Mus musculus
Regulation of pyruvate dehydrogenase (PDH) complex	Mus musculus
Signaling by Retinoic Acid	Mus musculus
Succinyl-CoA Biosynthesis	Mus musculus