Mitochondrial protein degradation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPP40630TfamADPSubstrate of LONP1 (mitochondrial matrix)LONP1:substrate protein (mitochondrial matrix)LONP1 hexamerPiH2OSubstrate of LONP1 (mitochondrial inner membrane)LONP1:substrate protein (mitochondrial inner membrane)CLPXPCLPXP:substrate protein (mitochondrial matrix)Substrate of CLPXP (mitrochondrial matrix)AFG3L2:Zn2+ hexamerAFG3L2:substrate protein (mitochondrial matrix)Substrate of AFG3L2 (mitochondrial matrix)AFG3L2:substrate protein (mitochondrial inner membrane)Substrate of AFG3L2 (mitochondrial inner membrane)Smdt1AFG3L2:SPG7:SMDT1AFG3L2:Zn2+:SPG7:Zn2+ heterohexamerHTRA2 trimerHTRA2:NDUFA13Q9ERS2H2OQ9ERS2Q9ERS2Q9ERS2Q9ERS2Q9ERS2Q9ERS2Q9ERS2P12023APP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025