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Platelet glycoprotein Ib alpha chain
Summary
- UniProt ID
- O35930
- Gene Symbol
-
- Gp1ba
- Gene ID
- 14723
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Blood coagulation
- Cell adhesion
- Disulfide bond
- Glycoprotein
- Leucine-rich repeat
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Sulfation
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| membrane |
| plasma membrane |
| glycoprotein Ib-IX-V complex |
Sequence
MALLILLFLLPSPLHSQHTCSISKVTSLLEVNCENKKLTALPADLPADTGILHLGENQLGTFSTASLVHFTHLTYLYLDRCELTSLQTNGKLIKLENLDLSHNNLKSLPSLGWALPALTTLDVSFNKLGSLSPGVLDGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDLDTLYLQRNWLRTIPKGFFGTLLLPFVFLHANSWYCDCEILYFRHWLQENANNVYLWKQGVDVKDTTPNVASVRCANLDNAPVYSYPGKGCPTSSGDTDYDDYDDIPDVPATRTEVKFSTNTKVHTTHWSLLAAAPSTSQDSQMISLPPTHKPTKKQSTFIHTQSPGFTTLPETMESNPTFYSLKLNTVLIPSPTTLEPTSTQATPEPNIQPMLTTSTLTTPEHSTTPVPTTTILTTPEHSTIPVPTTAILTTPKPSTIPVPTTATLTTLEPSTTPVPTTATLTTPEPSTTLVPTTATLTTPEHSTTPVPTTATLTTPEHSTTPVPTTATLTTPEPSTTLTNLVSTISPVLTTTLTTPESTPIETILEQFFTTELTLLPTLESTTTIIPEQNSFLNLPEVALVSSDTSESSPFLNSDFCCFLPLGFYVLGLLWLLFASVVLILLLTWTWHVTPHSLDMEQSAALATSTHTTSLEVQRARQVTMPRAWLLFLQGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLGTVGIRYSGHSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 301 | O-linked (GalNAc...) threonine |
|
||
| 311 | O-linked (GalNAc...) threonine |
|
||
| 315 | O-linked (GalNAc...) threonine |
|
||
| 316 | O-linked (GalNAc...) threonine |
|
||
| 335 | O-linked (GalNAc...) serine |
|
||
| 339 | O-linked (GalNAc...) threonine |
|
||
| 348 | O-linked (GalNAc...) threonine |
|
||
| 358 | O-linked (GalNAc...) threonine |
|
||
| 377 | O-linked (GalNAc...) threonine |
|
||
| 382 | O-linked (GalNAc...) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| GP1b-IX-V activation signalling | Mus musculus |
| Intrinsic Pathway of Fibrin Clot Formation | Mus musculus |
| Platelet Adhesion to exposed collagen | Mus musculus |
| Platelet Aggregation (Plug Formation) | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2217 | Bernard-Soulier syndrome |
