Intrinsic Pathway of Fibrin Clot Formation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
C1q binding protein tetramerKNG:C1q binding protein tetramerKng2prekallikrein:kininogen:C1q binding protein tetramerKlkb1kallikrein:kininogen:C1q binding protein tetramerKng2Plasma kallikreinactivated kininogen:C1q binding protein tetramerF12factor XIIafactor XIfactor XI:GPIb-IX-V complexGPIb-IX-Vfactor XIa:GPIb:GPIX:GPV complexP16294P16294factor IXaP16294F8factor VIIIvon Willibrand factor multimerfactor VIII:von Willebrand factor multimeractivated thrombin (factor IIa)Factor IIa inhibitors (compounds):IIaFactor IIa inhibitors (compounds)Factor IIa inhibitors (peptide):IIaFactor IIa inhibitors (peptide)factor VIIIaF8factor VIIIafactor IXafactor VIIIa:factor IXafactor Xfactor XaCa2+F10F8factor VIIIa A1:A3-C1-C2P97290P97290kallikrein:C1Inhfactor XIIa:C1Inhkallikrein:alpha2-macroglobulinA2M tetramer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025