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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Interleukin-1 receptor-associated kinase-like 2
Summary
- UniProt ID
- O43187
- Gene Symbol
-
- IRAK2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O43187
- PubChem
- O43187
- The Human Metabolome Database
- HMDBP09473
- The O-GlcNAc Database
- O43187
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of cytokine-mediated signaling pathway |
| protein phosphorylation |
| inflammatory response |
| intracellular signal transduction |
| GO Term |
|---|
| cytosol |
| endosome membrane |
| nucleus |
| cytoplasm |
| plasma membrane |
Sequence
MACYIYQLPSWVLDDLCRNMDALSEWDWMEFASYVITDLTQLRKIKSMERVQGVSITRELLWWWGMRQATVQQLVDLLCRLELYRAAQIILNWKPAPEIRCPIPAFPDSVKPEKPLAASVRKAEDEQEEGQPVRMATFPGPGSSPARAHQPAFLQPPEEDAPHSLRSDLPTSSDSKDFSTSIPKQEKLLSLAGDSLFWSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLHGLEIIHSNVKSSNVLLDQNLTPKLAHPMAHLCPVNKRSKYTMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNNRSPVYLKDLLLSDIPSSTASLCSRKTGVENVMAKEICQKYLEKGAGRLPEDCAEALATAACLCLRRRNTSLQEVCGSVAAVEERLRGRETLLPWSGLSEGTGSSSNTPEETDDVDNSSLDASSSMSVAPWAGAATPLLPTENGEGRLRVIVGREADSSSEACVGLEPPQDVTETSWQIEINEAKRKLMENILLYKEEKVDSIELFGP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| IRAK2 mediated activation of TAK1 complex | Homo sapiens |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Homo sapiens |
| Interleukin-1 signaling | Homo sapiens |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Homo sapiens |
| MyD88 cascade initiated on plasma membrane | Homo sapiens |
| MyD88 dependent cascade initiated on endosome | Homo sapiens |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | Homo sapiens |
| NOD1/2 Signaling Pathway | Homo sapiens |
| SARS-CoV-1 activates/modulates innate immune responses | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
