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E3 SUMO-protein ligase PIAS3

Summary

UniProt ID

O54714

Gene Symbol

Pias3

Organism

Mus musculus (house mouse)

External Links

PubChem: O54714
The O-GlcNAc Database: O54714

Annotation

Keyword

Alternative splicing
Cytoplasm
Isopeptide bond
Nucleus
Reference proteome
Transcription regulation
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
positive regulation of gene expression
negative regulation of gene expression
negative regulation of osteoclast differentiation
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of protein sumoylation
negative regulation of transcription by RNA polymerase II
regulation of transcription by RNA polymerase II
negative regulation of DNA-templated transcription
protein sumoylation
negative regulation of protein sumoylation

Displaying **all 8** entries
GO Term
chromatin
nucleus
cytoplasm
dendrite
nuclear speck
glutamatergic synapse
presynaptic cytosol
postsynaptic cytosol

Displaying **all 7** entries
GO Term
zinc ion binding
transcription coregulator activity
potassium channel regulator activity
transmembrane transporter binding
SUMO transferase activity
ionotropic glutamate receptor binding
SUMO ligase activity

Annotation information from UniProt.

Sequence

MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSAVQEGIQPESKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDTLGHFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
309	G49108TO	The O-GlcNAc Database
314	G49108TO	The O-GlcNAc Database
318	G49108TO	The O-GlcNAc Database
471	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Formation of Incision Complex in GG-NER	Mus musculus
SUMOylation of DNA replication proteins	Mus musculus
SUMOylation of immune response proteins	Mus musculus
SUMOylation of intracellular receptors	Mus musculus
SUMOylation of transcription cofactors	Mus musculus
SUMOylation of transcription factors	Mus musculus