SUMOylation of intracellular receptors

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
SUMO1:C93-UBE2IUbe2iARP19091ESR1P19785NR1H2:hydroxycholesterolSUMO2,3-NR1H2:hydroxycholesterolUBE2I:SUMO2,UBE2I:SUMO3NR1H3:hydroxycholesterolSUMO2,3-NR1H3:hydroxysterolNR1H4:chenodeoxycholatemonoSUMO1-NR1H4:chenodeoxycholateSUMO3:UBE2ISUMO3-NR1I2:rifampicinNR1I2:rifampicinNR3C1:(ALDO,11DCORST,CORST,CORT) dimer2SUMO1:NR3C1:Glucocorticoid ligand dimerQ8VII8Q8VII8P33242NR5A1SUMO2:UBE2IP33242NR5A2:cis-bicyclo(3.3.0)oct-2-enemonoSUMO1-NR5A2:cis-bicyclo(3.3.0)oct-2-enePparaPparaPGRQ00175P11416RaraRoraRoraRoraRXRAP28700THRAP63058P63058THRBP37242P37242VDRP48281
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O54714 E3 SUMO-protein ligase PIAS3
  • Pias3
view
P06537 Glucocorticoid receptor
  • Grl
  • Grl1
  • Nr3c1
view
P19785 Estrogen receptor
  • Esr
  • Esr1
  • Estr
  • Estra
  • Nr3a1
view
P28700 Retinoic acid receptor RXR-alpha
  • Nr2b1
  • Rxra
view
Q6NZM9 Histone deacetylase 4
  • Hdac4
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025