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Retinoic acid receptor RXR-alpha

Summary

UniProt ID

P28700

Gene Symbol

Nr2b1
Rxra

Gene ID

20181

Organism

Mus musculus (house mouse)

External Links

PubChem: P28700
The O-GlcNAc Database: P28700
Re-Glyco: P28700

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
DNA-binding
Direct protein sequencing
Isopeptide bond
Mitochondrion
Nucleus
Phosphoprotein
Receptor
Reference proteome
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
nucleus
mitochondrion
nucleoplasm
transcription regulator complex
RNA polymerase II transcription regulator complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
positive regulation of translational initiation by iron
ventricular cardiac muscle cell differentiation
mesenchyme development
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
regulation of branching involved in prostate gland morphogenesis
angiogenesis involved in coronary vascular morphogenesis
visceral serous pericardium development
negative regulation of transcription by RNA polymerase II
regulation of transcription by RNA polymerase II
heart development

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GO Term
zinc ion binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA binding
DNA-binding transcription factor activity
chromatin DNA binding
identical protein binding
sequence-specific DNA binding
transcription coactivator binding

Annotation information from UniProt.

Sequence

MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
432			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 16 in total

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Pathway Name	Organism
Carnitine shuttle	Mus musculus
Cytoprotection by HMOX1	Mus musculus
Endogenous sterols	Mus musculus
LXRs regulate gene expression linked to cholesterol transport and efflux	Mus musculus
LXRs regulate gene expression to control bile acid homeostasis	Mus musculus
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Mus musculus
Nuclear Receptor transcription pathway	Mus musculus
Recycling of bile acids and salts	Mus musculus
Regulation of lipid metabolism by PPARalpha	Mus musculus
SUMOylation of intracellular receptors	Mus musculus

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:1682	congenital heart disease	Alliance of Genome Resources
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements