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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll-like receptor 5
Summary
- UniProt ID
- O60602
- Gene Symbol
-
- TLR5
- TIL3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Systemic lupus erythematosus
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| signaling receptor activity |
| pattern recognition receptor activity |
| interleukin-1 receptor binding |
Sequence
MGDHLDLLLGVVLMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQVLNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSFFSLAANSLYSRVSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVSLSVLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTEGCDEEEVLKSLKFSLFIVCTVTLTLFLMTILTVTKFRGFCFICYKTAQRLVFKDHPQGTEPDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRCLSDLNSALIMVVVGSLSQYQLMKHQSIRGFVQKQQYLRWPEDLQDVGWFLHKLSQQILKKEKEKKKDNNIPLQTVATIS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 37 | N-linked (GlcNAc...) asparagine |
|
||
| 46 | N-linked (GlcNAc...) asparagine |
|
||
| 245 | N-linked (GlcNAc...) asparagine |
|
||
| 342 | N-linked (GlcNAc...) asparagine |
|
||
| 422 | N-linked (GlcNAc...) asparagine | |||
| 595 | N-linked (GlcNAc...) asparagine |
|
||
| 598 | N-linked (GlcNAc...) asparagine |
|
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| IRAK4 deficiency (TLR5) | Homo sapiens |
| MyD88 cascade initiated on plasma membrane | Homo sapiens |
| MyD88 deficiency (TLR5) | Homo sapiens |
| Toll Like Receptor 5 (TLR5) Cascade | Homo sapiens |
