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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Semaphorin-7A
Summary
- UniProt ID
- O75326
- Gene Symbol
-
- SEMA7A
- CD108
- SEMAL
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011240
- GlyConnect
- GlyGen
- O75326
- PubChem
- O75326
- RaftProt
- O75326
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Developmental protein
- Differentiation
- Disease variant
- Disulfide bond
- GPI-anchor
- Immunoglobulin domain
- Inflammatory response
- Intrahepatic cholestasis
- Methylation
- Neurogenesis
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| axon extension |
| semaphorin-plexin signaling pathway |
| positive regulation of axon extension |
| axon guidance |
| integrin-mediated signaling pathway |
| negative chemotaxis |
| positive regulation of ERK1 and ERK2 cascade |
| GO Term |
|---|
| plasma membrane |
| membrane |
| external side of plasma membrane |
| GO Term |
|---|
| semaphorin receptor binding |
| chemorepellent activity |
| integrin binding |
Sequence
MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 105 | N-linked (GlcNAc...) asparagine |
|
||
| 154 |
|
|||
| 157 | N-linked (GlcNAc...) asparagine |
|
||
| 258 | N-linked (GlcNAc...) asparagine | |||
| 330 | N-linked (GlcNAc...) asparagine |
|
||
| 602 | N-linked (GlcNAc...) asparagine |
|
G10019LZ
G38663NM
G48414YA
G37881RL
G14796IU
G47748JZ
G82830MN
G80920RR
G62765YT
G31852PQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Other semaphorin interactions | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2377 | multiple sclerosis | |
| DOID:2797 | idiopathic interstitial pneumonia | |
| DOID:305 | carcinoma | |
| DOID:3070 | high grade glioma | |
| DOID:3071 | gliosarcoma | |
| DOID:3082 | interstitial lung disease | |
| DOID:322 | myelitis | |
| DOID:331 | central nervous system disease | |
| DOID:3328 | temporal lobe epilepsy | |
| DOID:3393 | coronary artery disease |
