Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mannose-P-dolichol utilization defect 1 protein
Summary
- UniProt ID
- O75352
- Gene Symbol
-
- MPDU1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Congenital disorder of glycosylation
- Disease variant
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Gene Ontology (GO)
| GO Term |
|---|
| protein folding |
| dolichol-linked oligosaccharide biosynthetic process |
| oligosaccharide biosynthetic process |
| GO Term |
|---|
| membrane |
| endoplasmic reticulum membrane |
Sequence
MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLPQVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLVMHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNGHTGQLSAITVFLLFGGSLARIFTSIQETGDPLMAGTFVVSSLCNGLIAAQLLFYWNAKPPHKQKKAQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | Homo sapiens |
| Defective MPDU1 causes CDG-1f | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9870 | galactosemia | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050570 | congenital disorder of glycosylation type I | |
| DOID:0060656 | autosomal recessive congenital ichthyosis 1 | |
| DOID:0080556 | congenital disorder of glycosylation Id | |
| DOID:0080558 | congenital disorder of glycosylation If | |
| DOID:0080568 | congenital disorder of glycosylation Iq | |
| DOID:10907 | microcephaly | |
| DOID:11634 | myxedema | |
| DOID:11771 | spontaneous ocular nystagmus |
